3434 results
The purpose of this study is to evaluate the safety and effectiveness of the Aveir wireless dual-chamber pacemaker system in the treatment of patients with slow or irregular heartbeats.
Objective: The primary objective of this study is to investigate interoceptive abilities in adolescents with AN. To capture the multidimensional perspective, interoceptive abilities will be studied on an accuracy, sensibility and awareness level.…
The primary objective of this secondary prevention study is to evaluate the efficacy, safety, pharmacodynamics, and pharmacokinetics of gantenerumab, an anti-amyloid antibody, in amyloid-positive, cognitively unimpaired participants at risk for or…
To determine the influence of the extent of surgery on disease control in CRSwNP patients
The main study objective is to examine the effect of the PTWD program on glycaemic control of lower-educated participants with T2D. The secondary objectives include the effect on medication use, use of care and T2D self-management behaviours. We…
Although this procedure has been performed for more than 20 years and clinical results after myectomy combined with AMVLE are satisfactory, very little is known about the effect of surgical myectomy intervention on the blood flow through the aortic…
To investigate the effects of Dobutamine on RV contractility and oxygen consumption in patients with pulmonary arterial hypertension (PAH).
The aim of the current study is to determine whether a *liberal* strategy of maintaining Hb concentrations above 9 g/dL would result in a different neurological outcome when compared to a *restrictive* approach to red-cell transfusion to avoid…
1. To evaluate the efficacy of a gait training program using an instrumented treadmill with virtual and augmented reality for improving gait adaptability in people in the chronic phase after stroke in an RCT. 2. To identify patient characteristics…
We will investigate how safe the study device DV3395-C1 is when it is taken in by healthy participants. We will also look at the passage (i.e., gastrointestinal transit time) and activation of the study device. For this, we will see if the device…
In this study we will confirm that a microbial intervention based on capsules containing autologous (own) lyophilized faecal matter (LFMT), taken daily for 3 month has beneficial effects on residual beta cell function (C-peptide secretion upon MMT)…
The aim of this study is to determine functional parameters of the maternal heart during the lactation period by echocardiography and to correlate these functional parameters with circulating hormones.
The aim of this present feasibility study is to determine the safety and preliminary accuracy by which we can intra-operatively detect residual disease in esophageal tumor and lymph nodes. This study is set up as a prospective multi-centre dose…
To draw definite conclusions about the effectiveness of omega-3 PUFA supplementation in anorexia nervosa patients a double-blinded, placebo-controlled randomized controlled trial (RCT) with a substantial sample size should be conducted. Prior to…
It is our hypothesis that one week of plaster cast treatment will give a better functional outcome score as Patient Rated Wrist Evaluation (PRWE) and a lower pain score at 6 weeks post injury and will be less costly as compared to the control group…
The aim of this study is to investigate the influence of repeated exposure to sweet and sweet-sour apple juices on sweet taste preferences of 2.5-3 years old children.
Is care as usual (CAU) with adjunct evidence-based prescription of exercise more effective than CAU alone in reducingdepressive symptoms in patients with major depressive disorder in the specialised mental health service setting?
In this study we aim to evaluate the feasibility of a mobile application guiding IBD patients during biologic treatment.
To investigate that low-dose HDR-brachytherapy of prostate cancer will make from an immunologically *cold* (no T-cell infiltrations) prostate cancer an immunologically *hot* (CD4 and CD8-cell infiltrations) tumor.
To explore the possibility of detecting mesenteric ischemia by 13C-butyrate, 13C-glucose, and 13C-glucose and D-butyrate breath testing by comparing the timing and concentration of the peak of expired 13CO2 and DHO.