3434 results
The objective of this study is to pilot this novel VR treatment for social interaction difficulties (VR-SOAP) in preparation of a subsequent randomized controlled trial (RCT). The aim of the study is threefold: 1) to investigate the feasibility and…
This study will assess whether alginate oligomers enhance the efficacy of anti-diarrheals, i.e. compounds that block intestinal ion and water secretion.
- To assess the in vitro memory T cell response to 20 therapeutic SARS-CoV-2 vaccine candidate synthetic long peptides (SLPs);- To assess the in vitro humoral immune response to 20 therapeutic SARS-CoV-2 vaccine candidate SLPs.
The main goal is to establish reference values of new clinical laboratory tests
To assess risk factors for cardiomyopathy and heart failure among lymphoma (HL and aggressive B-cell NHL) survivors, focusing on the independent and joint effects of doses of anthracycline-containing chemotherapy (doxorubicin) and rituximab as well…
The primary aim of this case series is to investigate the safety and efficacy of long-term DRG stimulation in reducing spasticity in patients with motor complete and incomplete SCI. The secondary aim concerns improving postural stability through…
- to explore the decline in renal concentration ability (RCA) in a Dutch population of lithium treated patient - to explore the decline in kidney function
The aim of this study is to evaluate investigate whether BCRL will improve in patients with BCRL undergoing DIEP-flap BR combined with an inguinal lymph node transplant have statistically significant improvement of their BCRL (primary objective),…
The aim of this study is to compare the success of horizontal bone augmentation treatments with autogenous bone harvested from the calvaria area and autogenous bone harvested from the mandibular ramus.
The primary objective of this pilot study is to investigate the feasibility of an intervention based on the Arm Activity Tracker that aims to increase arm use during daily life conditions in stroke patients. Secondary objective is to obtain…
The current study will assess the neurocognitive effects of ayahuasca on brain activity and neurometabolite concentration, and how these effects correlate with various measures assessing subjective state and cognitive flexibility.
To establish the accuracy of the Medtrum TouchCare Nano 14 CGM system compared to thecurrent gold standards i.e. established central laboratory technique (the StatStrip Xpress®monitoring system (Nova Biomedical, Waltham, WA), the accuracy of a…
The objective of this single arm interventional study is to determine if renal denervation performed in the distal main and first order branch renal arteries is as effective in reducing blood pressure as the procedural approach used in the SPYRAL…
Primary Objective: - To study the pharmacokinetics (CL, Vd, and F) of ciprofloxacin in cachectic elderly patients and compare with normal weight participants.Secondary Objective(s): - To assess the influence of covariates (such as TBW, LBW, serum…
The purpose of this study is to investigate how quickly and to what extent JNJ-64417184 is absorbed and eliminated from the body when it is given together with drugs that reduce the stomach acidity. The study also investigates how safe the new…
The primary objective of the study is to evaluate the safety, tolerability, PK, and PD of AL002 administered in single ascending doses in healthy participants and multiple doses in participants with mild to moderate AD.
To develop a prediction model for ICD-therapy in a study population of ICD and CRT-D patients using a multimodal dataset containing clinical and historical data from electronic health-records, remote monitoring-data, accelerometer-derived data and…
To determine the difference in change over time of cognitive function and brain magnetic resonance imaging (MRI) measurements between breast cancer survivors and cancer-free individuals.
The purpose of this study is to investigate how quickly and to what extend JZP-324 is absorbed and eliminated from the body (this is called pharmacokinetics). It will also be investigated how safe the new compound JZP-324 is and how well it is…
The main objective is to investigate the fixation of the Journey II XR BCR TKA in terms of micromotion of the femoral and tibial components over time measured by RSA. Secondary, this study aims to assess the effect of this BCR TKA on daily life…