No registrations found.
ID
Source
Brief title
Health condition
alterations in taste perception as result of diet
Sponsors and support
Intervention
Outcome measures
Primary outcome
Subjective measurements of liking an saltiness of different salt concentrations in food.
Secondary outcome
Subjective measurements of desire-to-eat several types of salty foods. Detection threshold of salt in water.
Background summary
Worldwide, the daily sodium intake is too high and this leads to an increased blood pressure and thereby an increased prevelance of cardiovasular disease. A reduction of sodium in foods results in a decrease in saltiness, which is often associated with a less palatable taste. In humans, the perception and preference for salt is learned by experience rather than by physiological factors. Preference for saltiness can change by repeated exposure, as shown before. A salt-reduced diet may increase the pleasantness when exposed to low salt concentations in food and may increase the sensitivity to saltiness.
This study is a substudy of a large controlled trial: "KaNa-001" at clinicaltrials.gov
Study objective
A salt-reduced diet leads to a shift in preference to lower salt concentrations in food.
Study design
Wk 0 (baseline), wk 1, wk 3, wk 5, wk 9 and wk 13.
Intervention
Subjects will be on a controlled sodium reduced diet (2 g sodium/day) for 13 weeks.
Inclusion criteria
Inclusion criteria for the intervention group of the “Salt” study:
1. Participation in the Ka/Na-trial*;
2. Willing to participate in the “Salt” study.
Inclusion criteria for the control group of the “Salt” study:
1. Drop-outs of Ka/Na-trial due to a too low blood pressure (SBP < 130 mm Hg).
*This study is a sub-study of the KaNa-trial in which the effect of potassium and sodium on bloodpressure are investigated.
Exclusion criteria
N/A
Design
Recruitment
Followed up by the following (possibly more current) registration
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL3124 |
| NTR-old | NTR3274 |
| CCMO | NL39002.081.11 |
| ISRCTN | ISRCTN wordt niet meer aangevraagd. |
| OMON | NL-OMON35225 |