Pre-hospitale sepsis studie.

The study is a randomized clinical trial. All ambulances are equiped with lactate scouts. When patients meet the inclusion criteria they will be randomised by particular envelop. The patients in the intervention group, without allergies, will receive augmentin 1,2 gr i.v. within 30 minutes. The controle group will receive no antibiotics. We expect to include 300 patients per year with severe sepsis into our study, devided in two groups. The date of mortality of both groups will be collected and compared when admitted to Albert Schweitzer hospital. The follow up is until discharge or death. The patients who are admitted to the ICU will be compared with the APACHE/NICE score.
Objective of the studie: To give answers to the following questions: 1) Will prehospital treatment with augmentin 1,2 gr v.v.reduce the mortality in patients with severe sepsis? 2) What is the real percentage of septic patients who are suspected to have a severe sepsis in pre hospital phase? 3a) Is there a difference in lactate measurement after prehospital treatment and is it reliable? 3b) Is there a difference in blood cultures taken before and after the augmentin 1,2gr i.v.

Prehospital sepsis treatment with antibiotics in severe sepsis reduces mortality.

Date of enrollment of the first participant 1-11-2012.
The follow up is until discharge or death.

The pre-hospital treatment group will receive 1,2 gr augmentin iv. within 30 minutes. The control group will receive no antibiotics. Before giving the augmentin, blood cultures will be taken.