The primary objective of the present trial is to evaluate, during a 4-week period, the efficacy of a Zendium dentifrice containing enzymes, colostrum, lysozyme & zinc, in combination with the use of a manual toothbrush with respect to plaque…
ID
Bron
Aandoening
Gingivitis and plaque
Ondersteuning
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
1. BOMP (bleeding on marginal probing) - Van der Weijden 1994;<br>
2. Plaque Index - Quigley & Hein 2007.
Achtergrond van het onderzoek
Control of plaque on the tooth surfaces is the most important method of controlling dental disease. A manual toothbrush is the most popular mechanical method of plaque control. This non-specific control of the periodontal microbiota is effective in the majority of cases where access to the plaque deposits is possible (Listgarten 1988). In spite of the activity in improving toothbrush type and design, most people reduce plaque scores only with approximately 50% when they brush their teeth (Jepsen 1998). The development of a dentifrice that would allow the average person in helping to control plaque and gingivitis would be desirable.
Doel van het onderzoek
The primary objective of the present trial is to evaluate, during a 4-week period, the efficacy of a Zendium dentifrice containing enzymes, colostrum, lysozyme & zinc, in combination with the use of a manual toothbrush with respect to plaque removing efficacy, plaque growth inhibition, and effect on gingival inflammation.
Onderzoeksopzet
Time point:
1 visit: BOMP Plaque Index;
2 visit: BOMP Plaque Index;
3 visit: BOMP Plaque Index and VAS.
Onderzoeksproduct en/of interventie
Group 1: Experimental zendium dentifrice based on mild enzym complex non-SLS zendium;
Group 2: Regular zendium non SLS;
Group 3: Colgate SLS dentifrice;
Group 4: Sensodyne SLS dentifrice.
The intervention will have a duration of 4 weeks in which the participants have 2 visits.
Publiek
Afdeling CPT- Parodontologie<br>
Gustav Mahlerlaan 3004
G.A. Weijden, van der
Amsterdam 1081 LA
The Netherlands
+31 (0)20 5188307
ga.vd.weijden@acta.nl
Wetenschappelijk
Afdeling CPT- Parodontologie<br>
Gustav Mahlerlaan 3004
G.A. Weijden, van der
Amsterdam 1081 LA
The Netherlands
+31 (0)20 5188307
ga.vd.weijden@acta.nl
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
1. > 18 years;
2. Systemically healthy;
3. Minimum 5 teeth per quadrant;
4. Moderate gingivtis (40% bleeding on marginal probing);
5. Not participate in other oral clinical care study;
6. An absence of oral lesions and/or periodontal pockets ≤ 5 mm.
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
1. The absence of pregnancy and systemic diseases such as aids, cirrhosis, diabetes;
2. The absence of any adverse medical history or long-term medication;
3. Or any physical condition that limits manual dexterity.
Opzet
Deelname
Opgevolgd door onderstaande (mogelijk meer actuele) registratie
Andere (mogelijk minder actuele) registraties in dit register
Geen registraties gevonden.
In overige registers
| Register | ID |
|---|---|
| NTR-new | NL2524 |
| NTR-old | NTR2642 |
| CCMO | NL33561.018.10 |
| ISRCTN | ISRCTN wordt niet meer aangevraagd. |
| OMON | NL-OMON34372 |