We hypothesize that Hyperspectral imaging and thermal imaging are optimal techniques to measure tissue perfusion, and in this way diagnose peripheral arterial disease and to determine the effect of the treatment.
ID
Bron
Verkorte titel
Aandoening
Peripheral arterial disease, PAD, Hyperspectral imaging, thermal imaging, tissue perfusion, tissue ischemia, wound healing
Ondersteuning
Hanzeplein 1, 9713 GZ Groningen
The Netherlands
IJsseldijk 222, 2924 AZ Krimpen aan den IJssel
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
To determine normal ranges for oxyhemoglobin, deoxyhemoglobin, oxygen saturation and local skin temperature values during all stages and phases (pre-/per-/post-intervention) of treatment of peripheral arterial disease.
Achtergrond van het onderzoek
To detect and determine the severity of PAD, effective diagnostics are necessary. Current diagnostic methods used for PAD can only detect arterial inflow but do not measure tissue perfusion, which has a crucial meaning for the clinical outcomes. Hyperspectral imaging is a novel, non-invasive method to determine tissue perfusion by measuring oxyhemoglobin, deoxyhemoglobin and oxygen saturation transcutaneous. Additionally, thermal imaging is a non-invasive method to determine local changes in skin temperature, which correlates with vascular disease and ulceration. Therefore, we hypothesize that hyperspectral imaging and thermal imaging can be used to assess tissue perfusion during the complete care process of patients with peripheral arterial disease.
Doel van het onderzoek
We hypothesize that Hyperspectral imaging and thermal imaging are optimal techniques to measure tissue perfusion, and in this way diagnose peripheral arterial disease and to determine the effect of the treatment.
Onderzoeksopzet
Before, during and after treatment.
Onderzoeksproduct en/of interventie
none
Publiek
Wetenschappelijk
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
Patients with Peripheral arterial disease, with Rutherford classification 2 to 6 and patients with undefined ulcers meet inclusion criteria.
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
A potential subject who meets any of the following criteria will be excluded from participation in this study:
Patients with insufficient knowledge of the Dutch language, illiteracy or language barrier
Patients with severe peripheral oedema (will affect hyperspectral imaging and TcPO2)
Patient with severe cardiac-pulmonary failure
Patients with active cellulitis-erysipelas of the legs or other dermatological diseases (that will compromise tcPO2 of hyperspectral imaging measurements).
Opzet
Deelname
Opgevolgd door onderstaande (mogelijk meer actuele) registratie
Andere (mogelijk minder actuele) registraties in dit register
Geen registraties gevonden.
In overige registers
| Register | ID |
|---|---|
| NTR-new | NL7471 |
| NTR-old | NTR7713 |
| CCMO | NL68848.042.19 |
| OMON | NL-OMON48324 |