Mitochondrial capacity measured using different, non-invasive techniques can be used to analyse mitochondrial capacity in future studies
ID
Bron
Verkorte titel
Aandoening
Ageing, Sarcopenia, Mitochondrial Function
Ondersteuning
Wageningen University and Research
Human and Animal Physiology
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
The primary objective of this study is to measure mitochondrial capacity using NIRS in order to verify if NIRS can be used to analyse differences in training status in a normal student population.
Doel van het onderzoek
Mitochondrial capacity measured using different, non-invasive techniques can be used to analyse mitochondrial capacity in future studies
Onderzoeksopzet
Cross-sectional study design
Onderzoeksproduct en/of interventie
Cross-sectional study design in which subject will be selected on training status.
Publiek
Zodiac, Building 122, Room E0253
Bart Lagerwaard
De Elst 1
Wageningen 6708 WD
The Netherlands
+31 630599129 (Cell), +31 317 482 643 (Office)
bart.lagerwaard@wur.nl
Wetenschappelijk
Zodiac, Building 122, Room E0253
Bart Lagerwaard
De Elst 1
Wageningen 6708 WD
The Netherlands
+31 630599129 (Cell), +31 317 482 643 (Office)
bart.lagerwaard@wur.nl
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
• 18-28 year old male
• BMI 18.5-25 kg/m2
• VO2max ≤ 47 mL/kg/min or VO2max ≥ 57 mL/kg/min
• Performed a valid VO2max test (In order for the test to be considered valid two out of three of the following conditions should be met: 1) The maximal heart rate is within 10 beats of the predicted maximum (220 – age) 2) A plateau in in VO2 was reached; VO2 fails to increase with 150 mL/min, despite an increase in work load 3) Respiratory exchange ratio (RER) ≥ 1.00 has been achieved) and is has a
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
• Health concerns regarding respiratory and pulmonary diseases, such as COPD, (exercise induced) asthma and cardiovascular disease.
• (known symptoms of) Metabolic diseases, such as type I or II diabetes,
• Regular smoker (defined as smoking >5 cigarettes per week)
• Haemoglobin concentrations below 8.0 mmol/L
• Recent usage (within four months) of supplements with suggestive training effects, such as creatine phosphate, EPO or anabolic steroids.
• Usage of recreational drugs, such as marihuana, amphetamines and cocaine during the study (starting after first screening day)
• Suffers from (sport) injury that hampers maximal exercise performance
• Blood donation during the course of study
• Current participation in other clinical trials
• Employed or undertaking a thesis or internship at the department of Human and Animal Physiology
Opzet
Deelname
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In overige registers
| Register | ID |
|---|---|
| NTR-new | NL6296 |
| NTR-old | NTR6470 |
| CCMO | NL60823.081.17 |
| OMON | NL-OMON45254 |