NUTritional Route In Esophageal resectioN Trial.

The Nutrient Trial is a single arm feasibility trial investigating early oral intake after esophagectomy. Primarily the impact on anastomotic leakage and pneumonia rate and severitiy will be carefully monitored.

Early oral intake after esophagectomy is feasible and safe.

All primairy and secondary outcome measures are measured at the moment of discharge except for 2.

1. The caloric intake is measured on day 5 postoperative.

2. The hospital readmissions are determined within 30 days of discharge.

- De intervention consists of an oral intake scheme that is started from postoperative day one, under supervision of a dietician. Previously patients undergoing esophagectomy were kept nill-by-mouth untill day 5-7 postoperative, however, in this trial we will investigate if it is feasible and safe to start oral intake early after esophagectomy. In other wordt: patients will start a liquid diet from postoperative day 1, while previously they were not allowed to eat untill day 5-7 after the operation.


- There is no control group, for this is a single arm descriptive phase 2 trial.


- Duration of the intervention is not applicable to this study, because it consists of early oral intake. It is the timepoint that the oral intake is started that is relevant here.