Ingested protein derived amino acids are primarily used for synthesis of new protein, secondly all surplus is oxidized for energy. Exercise can influence protein metabolism and has shown in pilot experiments to reduce protein oxidation when exercise…
ID
Bron
Verkorte titel
Aandoening
protein metabolism, protein oxidation, breath test
Ondersteuning
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
Percentage of given protein oxidized over 5,5 hours
Doel van het onderzoek
Ingested protein derived amino acids are primarily used for synthesis of new protein, secondly all surplus is oxidized for energy. Exercise can influence protein metabolism and has shown in pilot experiments to reduce protein oxidation when exercise is given prior to the breath test.
Onderzoeksopzet
33 timepoints: a breath sample is given every 10 minutes, from 0 to 330 minutes
Onderzoeksproduct en/of interventie
Cycling: Submaximal Astrand test, 15 minutes of 30% at VO2max and 15 minutes of 60% at VO2max
Publiek
Gerlof Reckman
Groningen 9713 GZ
The Netherlands
06 57 27 54 11
g.a.r.reckman@umcg.nl, g.a.r.reckman@pl.hanze.nl
Wetenschappelijk
Gerlof Reckman
Groningen 9713 GZ
The Netherlands
06 57 27 54 11
g.a.r.reckman@umcg.nl, g.a.r.reckman@pl.hanze.nl
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
Male
Age between 18 – 30 years
Be able to fast overnight
Be able to consume a 500 ml test drink within 5 minutes
Be able to fast for 5.5 hours
Body Mass Index between 20 and 25 kg/m2
Be able to speak the Dutch language and give written consent
Score ‘low risk’ on the ASCM Risk Classification form
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
Disease and/or being medically treated (e.g. diabetes mellitus)
Heart condition
Milk (protein) allergy or intolerance
Smoking
Drug use
Alcoholism, and no alcohol during the 4-day diets
Waist circumference ≥102 cm
Opzet
Deelname
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In overige registers
Register | ID |
---|---|
NTR-new | NL6023 |
NTR-old | NTR6154 |
CCMO | NL59615.042.16 |
OMON | NL-OMON45714 |