Computer based cognitive flexibility training after stroke

Main: We expect that cognitive flexibility training will result in a larger improvement in objective executive functioning compared with those who receive mock training or those who are in the waiting list group.
Secondary: It is predicted that cognitive flexibility training will be more effective in stroke patients compared with healthy adults and more effective in the post-acute phase than in the chronic phase post-stroke. Moreover, we expect that cognitive improvement will be related to changes in brain activity. In particular, we expect that resting-state brain activity of stroke patients who receive cognitive flexibility training will converge more to “normal” than of those who did not receive this training.
Explorative: We will explore which lesion characteristics (e.g. type of stroke, size of lesion, brain regions), and other variables (e.g. IQ, age, comorbidities, cognitive flexibility at baseline) predict good outcome.

The groups will be compared immediately before training, after 6 weeks of training, immediately after, and 4 weeks after training.

Online cognitive flexibility training, online mock training (active control), or waiting list. The training duration is 12 weeks, five times per week for 30 minutes per session.
The cognitive flexibility training includes tasks that train attention, reasoning, and working memory. The participants will frequently switch between these tasks to assure that cognitive flexibility is needed. The mock training consists of tasks that do not train cognitive functioning and no frequent switches between tasks.

Uva.braingymmer.com is used for both training groups.