The effect of blood flow restriction with and without resistance exercise on muscle protein synthesis

The combined application of blood flow restriction and low load resistance exercise has been found to stimulate muscle protein synthetic rate to a similar extent as the traditional high load resistance exercise without blood flow restriction. However, it is still unclear whether blood flow restriction alone (without exercise) is a strong enough stimulus to significantly increase muscle protein synthesis.

The main aim of the current study will be to assess the effect of acute blood flow restriction and blood flow restriction combined with resistance exercise on the muscle protein synthetic rate in healthy young male subjects

The early (0-2h), late (2-5h) and total (0-5h) muscle protein synthesis

Blood flow restriction of lower extremity with or without low load resistance exercise