Patients in the home situation will mostly inhale forcefully through the TIP inhaler. A forceful inhalation is associated with cough A slow and deep inhalation using TIP results in a reduction of cough and more effective completion of a full…
ID
Bron
Verkorte titel
Aandoening
Cystic Fibrosis
Taaislijmziekte
Inhalationprofile
Inhalatieprofiel
Deposition
Depositie
Ondersteuning
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
The main study parameter is the percentage of patients who inhale with a slow/ intermediate/ fast inhalation maneuver while inhaling TIP.
Doel van het onderzoek
Patients in the home situation will mostly inhale forcefully through the TIP inhaler.
A forceful inhalation is associated with cough
A slow and deep inhalation using TIP results in a reduction of cough and more effective completion of a full inhalation maneuver
Patients inhale with a wide variation of tidal volumes while inhaling from a nebulizer
Onderzoeksopzet
?
Onderzoeksproduct en/of interventie
During the second home visit patients will be instructed to inhale as fast as possible, either the first or the second pair of four inhalations of tobramycin capsules. They will also be asked to inhale from a nebuliser with 0,9% NaCl solution for 10 minutes
Publiek
Dr. Molewaterplein 60
H.A.W.M. Tiddens
Dr. Molewaterplein 60
Rotterdam 3015 GJ
The Netherlands
+31 (0)10 4636690 / +31 (0)10 4636363 (general)
h.tiddens@erasmusmc.nl
Wetenschappelijk
Dr. Molewaterplein 60
H.A.W.M. Tiddens
Dr. Molewaterplein 60
Rotterdam 3015 GJ
The Netherlands
+31 (0)10 4636690 / +31 (0)10 4636363 (general)
h.tiddens@erasmusmc.nl
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
Proven CF
Maintenance treatment with TIP
Age of 6 and older
Informed consent by parents or patients
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
Respiratory tract exacerbation at time of TIP month defined as treatment with intravenous antibiotics
Any other acute condition such as otitis media which according to the treating physician will increase the risk of cough during the inhalation maneuvers.
Inability to follow instructions
Opzet
Deelname
Opgevolgd door onderstaande (mogelijk meer actuele) registratie
Andere (mogelijk minder actuele) registraties in dit register
Geen registraties gevonden.
In overige registers
| Register | ID |
|---|---|
| NTR-new | NL5080 |
| NTR-old | NTR5212 |
| CCMO | NL53582.078.15 |
| OMON | NL-OMON43918 |