Is a transversus abdominis plane block more effective regarding postoperative pain than perioperative wound infiltration with a long acting local anesthetic for a group of patients for open inguinal hernia repair
ID
Bron
Aandoening
Elective mentally competent surgical patients for open inguinal hernia repair in daytime surgery
De onderzoekspopulatie bestaat uit wilsbekwame proefpersonen ouder dan 18 jaar die zich op de preoperatieve screening van de polikliniek van de afdeling anesthesiologie in het Westfriesgasthuis presenteren voor een operatieve correctie van een liesbreuk volgens Lichtenstein en die voldoen aan de in en exclusie criteria zoals hieronder vermeld. De proefpersonen worden geïncludeerd na informed consent.
Ondersteuning
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
Analyse difference in numeric rating scale between the 2 groups until 48 hours after the operation
Achtergrond van het onderzoek
Hernia inguinal repair is the most common operation performed by general surgeons in the Netherlands. One of the most common complications after hernia repair is postoperative and chronic pain. Postoperative pain is an expected but indesirable effect after an operation, which can result in an prolonged hospital stay or longer time to return to full normal daily activities. Thera are indications that an insufficiant treatment of postoperative pain is a risk factor for persistant or chronic pain after open hernia repair. The objective of this study is to determine, whether the use of an perioperative echo guided unilateral TAP block has an superior effect on postoperative pain after open hernia inguinal repair compared to wound infiltration with a long acting local anesthetic. There wil be no further analysis in this study regarding the relation of open hernia repair and chronic pain
Doel van het onderzoek
Is a transversus abdominis plane block more effective regarding postoperative pain than perioperative wound infiltration with a long acting local anesthetic for a group of patients for open inguinal hernia repair
Onderzoeksopzet
NRS rating scale 48 hours post surgery
Leiden Perioperative care Patient Satisfaction questionnaire (LPPSq)
Onderzoeksproduct en/of interventie
Procedure/surgery: TAP block
2groups, group A a TAP block with 20ml of levobupivacaine 0,5% and subcutaneous wound infiltration with 20ml sodium chloride (to blind patient and physician) and group B, TAP block with 20ml sodium chloride and subcutaneous wound infiltration with 20ml levobupivacaine 0,5% (to blind patient and physician)
Publiek
Peter Dijkhuizen
Maelsonstraat 3
Hoorn 1624NP
The Netherlands
0229855427
p.dijkhuizen@westfriesgasthuis.nl
Wetenschappelijk
Peter Dijkhuizen
Maelsonstraat 3
Hoorn 1624NP
The Netherlands
0229855427
p.dijkhuizen@westfriesgasthuis.nl
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
Male patients, Age between 18-80 years (18-80 jaar), mentally competent, American Society of Anesthesiologists (ASA) class score 1-3, elective surgery, Body Mass Index (BMI) between 20 en 35.
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
Body Mass Index (BMI) >35, fever, coagulation disorders ( PT>13 sec en APPT >32 sec), renal insufficiency(eGFR< 50 ml/min), serious hepatic impairment(albumine <30g/L and or INR>2), woundinfection close to punction site, preoperative use of analgetics, hypersensitivity for Levobupivacaïne
Opzet
Deelname
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In overige registers
Register | ID |
---|---|
NTR-new | NL5386 |
NTR-old | NTR5487 |
CCMO | NL49853.094.14 |
OMON | NL-OMON42102 |