An observational study to obtain a comprehensive overview of long-term (≥5 years after burn injury) consequences after burn injuries, both in all patients admitted to burn centre admissions and in a subgroup of patients who suffered from…
ID
Bron
Verkorte titel
Aandoening
Long-term consequences of burns
Ondersteuning
Association of Dutch Burn Centres (ADBC)
P.O. Box 1015
1940 EA Beverwijk
Grant number: 15.102
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
Long-term generic HRQL of children and adult burn survivors will be assessed by the ‘EuroQol-5D-5L + cognitive domain’ (EQ-5D-5L).
Achtergrond van het onderzoek
SUMMARY
Rationale: Burden of disease calculations are an important resource in public health. The burden of disease aggregates all health consequences of a disease in one metric and is increasingly used for priority setting in health care, surveillance and interventions. For the calculation of the burden of disease, information on long-term consequences of the specific disease is needed. Currently, little is known about the long-term consequences and secondary conditions after burns. Therefore, calculation of the burden of burns is challenging.
Objective: To obtain a comprehensive overview of long-term (≥5 years after burn injury) consequences after burn injuries, both in all patients admitted to burn centre admissions and in a subgroup of patients who suffered from more extensive burns.
Study design: A multicentre cross-sectional study.
Study population: All burn patients (children and adults) who have been admitted to one of the three Dutch burn centres in the period August 2011 – July 2013 and with a hospital stay of more than one day or who have had surgical treatment for their burns.
For the cohort on extensive burns: all patients with extensive burns (over 20% total body surface area (TBSA)) in adults, over 10% TBSA in children <10 years or adults >50 years or TBSA third degree > 5% who had an admission to one of the three Dutch burn centres in the period 2010 – 2013.
Intervention (if applicable): Not applicable
Main study parameters/endpoints: To assess long-term health-related quality of life and long-term functioning, activities and participation of burn survivors, questionnaires that include questions on health-related quality of life, on body functioning, on participation and on environmental factors will be assessed in all patients.
In addition, to fully elucidate long-term consequences of extensive burns, muscular strength, aerobic capacity, contractures, body composition, fatigue, and habitual physical activity will be assessed in patients with extensive burns.
Doel van het onderzoek
An observational study to obtain a comprehensive overview of long-term (≥5 years after burn injury) consequences after burn injuries, both in all patients admitted to burn centre admissions and in a subgroup of patients who suffered from more extensive burns.
Onderzoeksopzet
Outcomes will assessed once. At least 5 years after burns.
Onderzoeksproduct en/of interventie
None
Publiek
Wetenschappelijk
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
- Patients of all ages with a hospital stay of ≥1 night or with surgical treatment for their burns in the period August 2011 – July 2012
- Informed consent
For the extended cohort on severe burns:
- Patients (≥10 - ≤50 years old) with major burns (over 20% TBSA)
- Patients (<10 and >50 years old) with major burns (over 10% TBSA)
- Patients with TBSA third degree > 5%
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
Insufficient knowledge of the Dutch language
Deceased
Opzet
Deelname
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In overige registers
Register | ID |
---|---|
NTR-new | NL6249 |
NTR-old | NTR6407 |
CCMO | NL59981.101.16 |
OMON | NL-OMON43284 |