The Lymphoma InterVEntion: personalized feedback and a self-management intervention to improve patient reported outcomes

Patients with lymphoma are at risk of experiencing adverse problems, with up to a quarter reporting psychological distress. Greater resources for coping with the cancer experience can reduce the risk for poor psychological health. Personalized feedback and a web-based self-management intervention provide patients with knowledge and skills, which might improve empowerment and increase active participation to self-manage their symptoms, since time spent with a health care professional is limited.

The purpose of this study is to develop an intervention for patients with lymphoma to reduce the impact of psychological problems that arise after diagnosis. The research question is whether personalized feedback and/or a self-management intervention compared with usual care is effective in reducing psychological distress and/or improving self-management skills and information provision.

Baseline (6 to 12 months after lymphoma diagnosis) and 16 weeks, 12 months and 24 months after baseline

The Lymphoma InterVEntion [LIVE] trial consists of two components: (1) the provision of personalized feedback to patients about their self-reported symptoms and quality of life in comparison with other age and sex-matched lymphoma patients and/or a norm population, and (2) a web-based self-management intervention Living with lymphoma directed at improving self-management skills and information provision, while reducing psychological distress. The provision of personalized feedback on PROs facilitates monitoring one’s own symptoms and functioning. The second component, Living with lymphoma, is an adaptation from BREAst cancer e-healTH (BREATH) for patients with breast cancer survivors and is based on cognitive behavioural therapy (CBT) components, such as psychoeducation and cognitive reframing and is directed to lymphoma patients.



The control group receives usual care.