Our hypothesis is that patients with micro and macrovascular potentially have a different geriatric profile (cognitive function, physical function, ADL dependency, negative outcomes)
ID
Bron
Verkorte titel
Aandoening
Memory complaints, microvascular damage, macrovascular damage
Ondersteuning
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
The main study parameters are different vascular phenotypes, based on measurements of macro- and microvascular function.
Achtergrond van het onderzoek
Rationale: There is a strong relationship between cardiovascular morbidity and the risk of functional decline. However, the effect of cardiovascular morbidity on cognitive and physical function in geriatric memory clinic patients is not precisely known.
Objective: to relate different vascular phenotypes, based on macro- and microvascular damage to changes in cognitive and physical status in a geriatric population.
Study design: observational longitudinal cohort study with a follow-up of 2 years.
Doel van het onderzoek
Our hypothesis is that patients with micro and macrovascular potentially have a different geriatric profile (cognitive function, physical function, ADL dependency, negative outcomes)
Onderzoeksopzet
baseline, 6 months, 12 months, 24 months.
Publiek
Wetenschappelijk
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
- Age of 65 years or older
- Signed informed consent for the general protocol (METc 2017.148)
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
- Insufficient proficiency of the Dutch language.
- Severe cognitive impairment: MMSE score < 16.
Opzet
Deelname
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In overige registers
| Register | ID |
|---|---|
| NTR-new | NL9856 |
| CCMO | NL73405.029.20 |
| OMON | NL-OMON52796 |