The following hypothesis will be investigated: - Casein ingested as calcium-caseinate results in a more rapid digestion and absorption, and subsequent whole body net protein balance, as compared to the ingestion of micellar casein. - The ingestion…
ID
Bron
Aandoening
protein digestion and absorption
milk proteins
whole-body protein synthesis
eiwitvertering
melkeiwitten
eiwitsynthese
Ondersteuning
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
exogenous phenylalanine appearance rates
Doel van het onderzoek
The following hypothesis will be investigated:
- Casein ingested as calcium-caseinate results in a more rapid digestion and absorption, and subsequent whole body net protein balance, as compared to the ingestion of micellar casein.
- The ingestion of a calcium-caseinate solution will result in a more rapid digestion and absorption, and subsequent whole body net protein balance, as compared to the ingestion of calcium-caseinate fibers.
Onderzoeksopzet
blood samples will be taken immediately before ingestion of the protein supplement (t=0), and at timepoints: 15, 30, 45, 60, 90, 120, 150, 180, 210, 240, 300 and 360 min.
Onderzoeksproduct en/of interventie
each subject will participate in one trial, randomly assigned. Intervention consists of the ingestion of an intrinsically labeled protein supplement: micellar casein, calcium caseinate, or caseinate fibers, whereafter regular blood samples are taken.
Publiek
Milou Beelen
P.O. Box 616
Maastricht 6200 MD
The Netherlands
T +31 (0)43 3881394
E Milou.Beelen@maastrichtuniversity.nl
Wetenschappelijk
Milou Beelen
P.O. Box 616
Maastricht 6200 MD
The Netherlands
T +31 (0)43 3881394
E Milou.Beelen@maastrichtuniversity.nl
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
- Males
- Aged between 18-35 years
- Healthy, recreationally active (participating in recreational sports activities ¡Ü 3 times per week)
- BMI < 25 kg/m2
- No physical limitations (i.e. able to perform all activities associated with daily living in an independent manner).
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
- Female
- Smoking
- Allergies to milk proteins
- Musculoskeletal disorders
- Use of any medications known to affect protein metabolism (i.e. corticosteroids, non-steroidal anti-inflammatories, or prescribed acne medications).
- Participation in any structured regular exercise program
- Chronic use of gastric acid suppressing medication or anti-coagulants
- Unstable weight over the last three months
- Pathologies of the gastrointestinal tract
Opzet
Deelname
Opgevolgd door onderstaande (mogelijk meer actuele) registratie
Andere (mogelijk minder actuele) registraties in dit register
Geen registraties gevonden.
In overige registers
| Register | ID |
|---|---|
| NTR-new | NL5110 |
| NTR-old | NTR5242 |
| CCMO | NL52798.068.15 |
| OMON | NL-OMON44783 |