126 resultaten
Liraglutide is an effective and safe treatment modality in metformin-treated patients suffering from schizophrenia with anti-psychotic drugs-related diabetes mellitus.
We hypothesize that the exposure to inulin will strengthen the resilience of the oral ecosystem such that 1) it will be able to withstand experimental gingivitis challenge by maintaining a more health-associated microbiome during this challenge and…
Ethanol lock therapy in TPN patients reduces the incidence of catheter-related infections and thrombosis.
In view of the poor prognosis of SSc, the presumed autoimmune origin, and the lack of available therapies, this disease is considered suitable for initial investigation of the tolerability and efficacy of anti B-cell therapy. In literature, there…
Hypothesis 1: Participants in both conditions (experimental and placebo) will show a reduction in gamble problem severity immediately post-intervention and at 3-and 6-month follow-ups. However, participants in the experimental condition will show a…
We hypothesize that iABM patients, relative to controls, will show less addiction problems, increased health, reduced physical and psychological complaints, and reduced use of health care post-intervention and at 6 & 12 month FU Further, we…
Inhibition of the H1 receptor will lead to an improvement of rectal sensitivity, followed by less abdominal symptoms in patients with irritable bowel syndrome.
Prevention of respiratory syncytial virus infection using palivizumab in preterm children with gestational age 32-35 weeks will result in decreased incidence of recurrent episodes of wheeze (post-bronchiolitis wheeze).
Extension of SAD PK/PD Model, confirmation of SAD PD effects
Vitamin D supplementation will improve glycemic control in patients with type 2 diabetes melliuts.
Single dose intranasal dexmedetomidine can be administered safely to elderly people as premedication with respects to hemodynamic changes, irrespective of the concurrent use of betablocking medication
the active treatment group has an improvement of at least 10 points of DASH functional outcome more than the placebo group.
The overall hypothesis is that balance-specific exercise training only improves postural control of sway measured in standing and causes retention of the improved sway behavior and that such behavioral improvements correlate with changes in measures…
1. Treatment resistant depression (TRD) is characterized by dopaminergic dysfunction as assessed with a fMRI Pavlovian learning task and [11C]Raclopride PET with amphetamine challenge; 2. Relative to placebo, current serotonergic and noradrenergic…
We hypothesize that unfractionated heparin could be of benefit in treatment of ALI. Delivering heparin directly to the pulmonary compartment may attenuate fibrin depositions more effectively while reducing the risk of bleeding as a result of…
Proximal serrated polyp detection rate is higher in endoscopists group who were trained by the e-learning.
The study will assess drug-induced change in performance in divergent thinking and goal-directed behaviour when comparing psilocybin to placebo, before and after an induction of stress. Additional study parameters include frontal-subcortical…
Although vitamin D is well known for its function in calcium homeostasis and bone mineralisation, several studies have shown an effect on pulmonary function and incidence of airway infections. Vitamin D deficiency is a common problem in patients…
We hypothesize that induction of trained immunity through BCG vaccination may improve host defence mechanisms of patients throughout the perioperative period.