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We hypothesize that the exposure to inulin will strengthen the resilience of the oral ecosystem such that 1) it will be able to withstand experimental gingivitis challenge by maintaining a more health-associated microbiome during this challenge and…
We hypothesize that our integrated care intervention, as compared to usual care and a placebo version of the m/eHealth intervention, will increase quality of life of KA patients by improving societal participation including work, indirectly reducing…
The hypothesis is that the metabolic age, representing a health score will be lower after nine weeks of personalized dietary intervention compared to the control arm (without dietary advice). The phenotypic flexibility or resilience (the ability to…
1. We hypothesize that post exercise whey protein ingestion will increase myofibrillar protein synthesis rates to a greater extent than collagen protein supplementation. 2. We hypothesize that post exercise collagen protein ingestion will increase…
BCG vaccination may induce (partial) protection against susceptibility to and/or severity of SARS-CoV-2 infection. This will lead to reduced workplace absenteism under health care workers taking care of patients with COVID-19
Proximal serrated polyp detection rate is higher in endoscopists group who were trained by the e-learning.
Based on Faber ea. 2006, we expect that the effectiveness of ‘In Balans’ can be replicated and extended in a group of community-dwelling pre-frail and non-frail older adults with an increased risk of falls, with a significant reduction of the number…
We hypothesize that our individual rehabilitation program will be (cost-)effective regarding the primary and secondary health- and work-related outcome measures of work in cancer survivors with an employment contract, compared to care as usual.…
We speculate that the virome composition of the lean donor and the subsequent interaction between phages and bacteria in the recipients are crucial determinants of stability and diversity of gut bacterial composition and glucose metabolism in humans…
Reduction of severity of personality disorder symptoms
Post-donation iron supplementation will be an effective strategy to enhance the iron status recovery in whole blood donors with low ferritin levels.
Due to its ability to avoid preterm birth, the neurodevelopmental sequelae of preterm birth could also be prevented by progesterone. However, progesterone may also exert direct effects on the fetus’ developing brain.
We hypothesize (hypothalamic) obesity can be treated with GLP-1 analogues in patients with craniopharyngioma.
The main objective of the study is to investigate if positional therapy during sleeping, using the LEFT device, reduces nighttime gastroesophageal reflux symptoms.
Sacroiliac joint infiltration with bupivacaine 0.25% is superior to placebo in reducing post-operative pain.
More physical activity will increase protein synthesis rates of muscle tissue and will decrease protein synthesis rates of prostate tissue and prostate tumor tissue.
Metformin combined with doxycycline will result in a better improvement in HS severity and the pre-diabetic condition of the patients compared to doxycycline monotherapy.
It is hypothesized that both caloric restriction and exercise lower tumor tissue protein synthesis rates but that exercise, as opposed to caloric restriction, will prevent a concomitant decline in muscle tissue protein synthesis rates.
CONFIRMATORY HYPOTHESIS Our novel cognitive training incorporates several aspects that are expected to increase its effectiveness when compared to traditional Cognitive Bias Modification (CBM). As a confirmatory hypothesis we expect that, as an add-…
Foods consisting of whole dairy, butter, beef and locally grown seasonal vegetables with a balanced composition of omega 3 and 6 fatty acids and a wide range of essential micronutrients and anti-inflammatory capacities have a protective effect on…