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We hypothesize that after 21 days of consuming GOS the component score of gut comfort in female adults of 25 – 45 years of age with self-reported gut related complaints is significantly lower (mean difference of at least 2 or more on the component…
Foods consisting of whole dairy, butter, beef and locally grown seasonal vegetables with a balanced composition of omega 3 and 6 fatty acids and a wide range of essential micronutrients and anti-inflammatory capacities have a protective effect on…
1) It is expected that the percentage of days abstinent will be higher in both training interventions compared to the sham ApBM with religion-adapted ApBM having the biggest effect-size in this comparison. Also, it is expected that participants with…
The pericapsular nerve group (PENG) block is superior to placebo 'sham' blocks in hip arthroplasty surgery in reducing patients pain scores (Numeric Rating Scale of 0 to 10), on the day of surgery
Predominantly sleeping in the non-supine position could improve oxygenation and thereby shorten the disease course in admitted COVID-19 patients.
1. Primary: To investigate the effect of internet-based cognitive behavioral therapy (e-CBT) in patients with high levels of preoperative anxiety and/or pain catastrophizing, on the risk of PPBCT six months after breast cancer surgery. e-CBT will be…
The study hypothesis is that the LSD group shows an increase in positive mood and subjective effects between baseline and follow-up after 4 weeks of repeated dosing with LSD compared to the placebo group. An additional study parameter is the…
1. We hypothesize that post exercise whey protein ingestion will increase myofibrillar protein synthesis rates to a greater extent than collagen protein supplementation. 2. We hypothesize that post exercise collagen protein ingestion will increase…
Ingestion of low glycated milk protein results in a greater muscle protein synthetic response compared to high glycated milk protein.
We expect an incidence of delirium in our control group of 30%. This is based on literature documenting incidence of delirium in neurosurgical patients in a northern European population of 29-33%. The expected effect cannot be based on previous…
Based on Faber ea. 2006, we expect that the effectiveness of ‘In Balans’ can be replicated and extended in a group of community-dwelling pre-frail and non-frail older adults with an increased risk of falls, with a significant reduction of the number…
CONFIRMATORY HYPOTHESIS Our novel cognitive training incorporates several aspects that are expected to increase its effectiveness when compared to traditional Cognitive Bias Modification (CBM). As a confirmatory hypothesis we expect that, as an add-…
We hypothesize that our individual rehabilitation program will be (cost-)effective regarding the primary and secondary health- and work-related outcome measures of work in cancer survivors with an employment contract, compared to care as usual.…
It is hypothesized that both caloric restriction and exercise lower tumor tissue protein synthesis rates but that exercise, as opposed to caloric restriction, will prevent a concomitant decline in muscle tissue protein synthesis rates.
Metformin combined with doxycycline will result in a better improvement in HS severity and the pre-diabetic condition of the patients compared to doxycycline monotherapy.
BCG vaccination may induce (partial) protection against susceptibility to and/or severity of SARS-CoV-2 infection. This will lead to reduced workplace absenteism under health care workers taking care of patients with COVID-19
We speculate that the virome composition of the lean donor and the subsequent interaction between phages and bacteria in the recipients are crucial determinants of stability and diversity of gut bacterial composition and glucose metabolism in humans…
Reduction of severity of personality disorder symptoms