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Intravenous immunoglobulin and intravenous methylprednisolone as optimal induction treatment in CIDP
Primary objective of this randomized controlled trial is to assess whether combining IVIg and methylprednisolone leads to more frequent long-term remission in CIDP compared to treatment with IVIg alone.
Several reports have indicated that the chemokine receptor CCR5 and its ligands, escpecially CCL5 (formerly known as RANTES), may play a role in the pathogenesis of psoriasis. CCR5 targeted treatment could therefore be a therapeutic option for…
Failure of discontinuation of off-label antipsychotics in people with intellectual disabilities is the result of (1) subjective interpretation of behavior by caregivers, influenced by fear of worsening of behavior after drug reduction, (2) a…
Daily ingestion of a nutritional supplement enriched with antioxidants during 8 weeks pulmonary rehabilitation results in a decreased oxidative stress in rest and after exercise in COPD patients compared to an iso-caloric placebo.
We hypothesize that prevenar 13 elicits a humoral immune response against oxidized low density lipoprotein
BB3 will improve kidney function in the immediate post-transplant period in patients who have received a DCD kidney transplantation.
1. Orthokin relieves symptoms of pain and dysfunction of OA as determined by the outcome of designated subjective scoring systems; 2. Orthokin reduces inflammatory markers in synovial fluid; 3. Orthokin inhibits long-term radiological progression of…
As the anterolateral approach is also a routine procedure, and to test how minimally invasive MIS is, we hypothesized that patients treated with a THA using a posterolateral or anterolateral MIS would experience superior clinical results compared…
1. A decrease in cocaine use over a three month period in participants who receive AAT training as opposed to VPT training. 2. A change in symptoms involving craving, the urge to use, withdrawals well as stated readiness to change in participants…
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Dose-escalation of paroxetine (up to 50 mg/day) does not increase efficacy of treatment of Major Depressive Disorder in patients who did not respond to a 6 week trial of paroxetine in a standard dose (20 mg/day).
1. In patients with a painful arc, treatment with hyaluronic acid and lidocaine, will give a mean improvement of 70 % of their pain at 26 weeks after start of the treatment with subacromial injection as compared to subacromial injection with a…
Hypothesis is that elderly patients, acutely admitted for hip fracture, treated with melatonin for 5 days will experience less delirium than patients treated with placebo.
We predict that the combination of the VR-GAIME and general aggression treatment will be more successful in reducing aggressive behavior.
Low dose nadroparin will prevent symptomatic and asymptomatic catheter-related deep vein thrombosis in patienten treated with high dose chemotherapy.
Supplementation with pyridoxine-5'-phosphate will not lead to an increase in plasma concentrations of pyridoxine
Patients with a wrist trauma represent a substantial part of the patient population at the Emergency Department. Most hospitals routinely carry out a radiological examination of patients following wrist trauma to exclude a distal radius fracture.…
This research project hypothesises that hyperoxic interval training improves whole body insulin resistance, endothelial dysfunction, cardiovascular fitness, lipid metabolism and glycemic control in the treatment of deconditioned non-insulin…
The ingestion of free amino acids will result in higher plasma amino acid concentrations, resulting in enhanced muscle protein synthesis rates when compared with the ingestion of milk.
OTR4120 will improve healing of chronic ulcers.