4587 resultaten
Administration of fluoxetine during late brain development (adolescence), but not in adulthood, will result in abnormal outgrowth of the 5-HT system. This long-lasting disturbance of the 5-HT system may be visualized using MRI techniques and can…
To study if a Mediterranean diet (MD) followed by lean donor fecal microbiota transplantation (FMT) has synergistic superior beneficial effects on peripheral insulin sensitivity and (small) intestinal microbiota composition as compared to…
The primary objective of this double blind study is to determine the effects of 1 mg, 4 mg, or 8 mg of ARA 290 administered subcutaneously for 28 consecutive days versus placebo on corneal nerve fiber density
In this multicenter RCT we aim to investigate the quality of fracture reduction and fixation, and patient-relevant outcomes when using the intra-operative use of the 3D-RX-system as compared to the conventional 2D-fluoroscopy in patients with…
1. We hypothesize that post exercise whey protein ingestion will increase myofibrillar protein synthesis rates to a greater extent than collagen protein supplementation. 2. We hypothesize that post exercise collagen protein ingestion will increase…
The main objective is to examine the efficacy of a combined errorless learning and Goal Management Training (GMT) intervention for treatment of executive problems of patients with acquired brain injury (ABI) in the chronic phase (>6 months…
A positive effect of a Growing Up Milk with added prebiotics or prebiotics and LCPUFA on the intestinal microbiota of toddlers.
The null hypothesis of this research is that the ZCQ outcome of PDI surgery is similar to the ZCQ outcome os surgical decompression at 1 year after surgery.
rhDNase targeted to the peripheral airways improves lung function in children with CF and a stable clinical condition.
- The incidence of PONV will be higher in the group receiving dexamethasone alone - There will be no significant difference in the incidence of PONV between the two groups receiving two anti-emetic drugs - There will be less postoperative agitation…
Inhibition of the H1 receptor will lead to an improvement of rectal sensitivity, followed by less abdominal symptoms in patients with irritable bowel syndrome.
In EPF, the sequential combination of mifepristone with misoprostol is superior to the use of misoprostol alone in terms of complete evacuation of products of conception, patient satisfaction, complications, side effects and costs.
Treatment with Botox will give a better healing rate for anal fissures compared to treatment with isosorbidedinitrate ointment.
The primary aim is to determine if there is a difference between tibolone and placebo or if there is a difference between raloxifene and placebo. The secondary aim is to determine if there is a difference between tibolone and raloxifene. Primary…
rTMS has a positive effect in the treatment of depression.
Implantation of aspheric IOL's results in higher visual performance than spheric IOL's.
• To evaluate the safety and tolerability of three oral dose levels of LTI-291 following 28 days of LTI-291 treatment in patients with Parkinson’s Disease with GBA-PD. • To characterize the plasma and CSF pharmacokinetics (PK) of LTI-291 following…
To study the effect of the interaction of cyclooxygenase-2 (COX-2) inhibition (started preoperatively and continued 5 days into the postoperative period) and extended local anaesthetic blockade via paravertebral block on postoperative central…
We hypothesize that treatment with peppermint oil will lead to a greater symptom (especially abdominal pain) reduction in IBS patients compared to placebo. This will lead to a higher total percentage of responders (as defined by FDA/EMA…
1. The primary research inquiry being raised concerns anaesthesia related causes: Is it possible that adapting an amount of Sevoflurane, from 1 MAC (minimum alveolar concentration) (2,5 vol%) to ½ MAC (1,25 vol%) in an MRI scan can reduce the…