289 resultaten
The self-help intervention Happy@Work will reduce symptoms of depression. The self-help intervention Happy@Work will be cost effective.
We hypothesize that peripheral perfusion targeted fluid management (PPTFM) might prevent excessive fluid administration, leading to less formation of tissue edema, less respiratory dysfunction and shorter duration of mechanical ventilation.
The purpose of the study is to conduct a randomised controlled trial with the onlinecourse 'Voluit Leven' as an intervention to study the: 1. Cost-effectiveness in terms of reduction of psychological symptoms (mood symptoms and disorders…
A constant Hb concentration will improve the quality of life of patiënts with a chronic need for bloodtransfusions.
Interferons (IFNs) are a family of cytokines which have important antiviral and antiproliferative properties. They also play an important role in immunomodulation. Type I IFNs have been implicated in autoimmune diseases, including systemic lupus…
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The aim of this study is to investigate the effectiveness and the cost-effectiveness of the individual CBT program the “D(o)epressie cursus” by means of the following hypotheses; 1. Is the individual CBT program the “D(o)epressie cursus” more…
An educational film seen before surgery change the postoperative expressed need for opioids by the patient (i.e., increase when postoperative patients report NRS > 4 and decrease when patients report NRS ≤ 4).
To evaluate the impact of three different implementation strategies for implementing IBSM in current clinical practice, we have proposed the following three hypotheses: 1. Hypothesis 1 (Reach): More general practices will participate in IBSM in the…
The hypothesis to be tested is the feasibility of arm A and arm B.
1. Providing children with tailored non-smoking advice will prevent them from becoming a smoker; 2. Children receiving tailored non-smoking advice will have stronger cognitions in favour of non-smoking; 3. Prompting children through e-mail and SMS…
The aim of the study is to compare the effectiveness of tocolysis with Nifedipine or Atosiban in pregnant women with threatened preterm labour with a gestational age between 25 – 34 weeks. We will look at neonatal mortality and morbidity, duration…
1. The STERK-intervention will prevent early onset of anxiety and mood disorders in offspring (compared to a minimal information condition); 2. The STERK-intervention is cost-effective; 3. The effectiveness of the STERK-training will be influenced…
Which of two strategies for early detection of depression in primary care performs best, i.e. results in higher number of identified depressions. The two strategies are: 1. Active case finding of high risk patients by a nurse practitioner; 2.…
Xenon wil provide improved hemodynamics in patients undergoing cardioverter defribrillator implantation.
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1. Muscle ultrasound is capable to detect dermatomyositis and polymyositis in suspected patients; 2. Muscle ultrasound is capable to detect improvement of structural muscle changes induced by treatment; 3. Muscle ultrasound is capable to detect…
The primary goal of this study is to determine whether it is possible to discontinue treatment with TNF blocking therapy in patients suffering from Rheumatoid Arthritis when the patient has had stable low disease activity.
The purpose of the study is to conduct a randomised controlled trial with the onlinecourse 'Voluit Leven' as an intervention to study the: 1. (Cost)effectiveness in terms of reduction of psychological symptoms (mood symptoms and disorders…
Increasing kidney function by kidney transplantation might improve the circadian rhythms of melatonin concentration, sleep and 24-hour blood pressure profile.