9 resultaten
To develop a dosing nomogram of irinotecan in patients homozygous polymorphic for UGT1A1*28 and/or UGT1A1*93 in order to reduce the incidence of severe irinotecan-associated toxicity, defined as febrile neutropenia in the first 2 cycles (amendment…
Treating a symptomatic urinary tract infection in patients with a long-term indwelling catheter for 5 days is non-inferior compared to the standard duration of 10 days of antibiotic therapy with regard to clinical cure rate.
Preventive group support for 6 to 8 years old children after parental divorce or separation, leads to: - more positive child functioning; - decreased emotional and behavioral problems of participating children; and - increased child wellbeing;
The use of SBAR by Community Nurses will improve their selfefficacy and empowerment.
Acutely hospitalized older patients frequently suffer from inadequate sleep. Insufficient sleep can lead to patient distress and delayed recovery from acute illness or a surgical procedure. Currently, no evidence-based treatments exist for sleeping…
1. A decrease in cocaine use over a three month period in participants who receive AAT training as opposed to VPT training. 2. A change in symptoms involving craving, the urge to use, withdrawals well as stated readiness to change in participants…
The majority of adolescents in the Netherlands has an inadequate consumption of fruit, vegetables, fibers and an excessive consumption of energy-dense, nutrition-poor foods. Unhealthy diets result in an increased risk of overweight, obesity and…
The aim of the study is to examine the effectiveness of Rock and Water (R&W) and possible moderators and mediators. Effectiveness: - The R&W program will increase students’ socio-emotional adjustment (i.e., psychosocial wellbeing,…
Primaire onderzoeksvragen1. Leidt een blootstellings-behandeling (T-BET) tot daling in tinnitus gerelateerde vrees en herstel (vermindering) van klachten en tinnitus-ernst in tinnitus patiënten, vergeleken met een maskerings-therapie?2. Kunnen we…