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First we have to define its association with current objective inflammatory parameters and its quality to sense small (subclinical) changes in a short treatment period. If this quality exists, than the Handscan might be a new tool for objective and…
We hypothesize that GABA could improve glucose tolerance and cardiovascular health after long-term supplementation
Botulin toxin driven treatment ylieds the highest efficacy when injected into the external anal sphincter.
This study will find the most effective and optimal resistance exercise training program for frail older adults, and takes into account (in)adequate protein intake and personal characteristics, in order to improve sarcopenia-related outcomes in this…
Early post-operative mortality is particularly high, with reported 30-day mortality rates of 7.5 - 13.3%. Up to 5% of the hip fracture surgeries is performed in patients with a high death within 30-days after surgery. If the preoperative mortality…
TKR with large migration in the last 2 PO years show a larger inducible migration compared with TKR with little to no migration in the last 2 PO years
It is hypothesised that this study leads to a personalised intervention program that improves medication adherence in people with type 2 diabetes mellitus that are non-adherent to their oral blood glucose lowering and/or antihypertensive medication.
It is expected that HBOT twice daily for five days is more effective than HBOT once daily for ten days.
treatment with the Straumann Bone Level Tapered implant are a reliable option for single tooth replacements in the maxillary aesthetic zone. No significant differences between patients with a preserved alveolar ridge or patients with a non-preserved…
We hypothesize that among breast cancer patients with a grade 3 breast fibrosis the RILA frequency is significantly lower compared to the RILA frequency among breast cancer patients with no fibrosis.
Treatment algorithm will lead to earlier identification of patients indicated for surgical reconstruction and exercise program.
The rationale behind the guideline recommended dose reduction of ciprofloxacin in patients with impaired renal function is to achieve bioequivalence, defined as drug exposure equivalent to exposure in patients with adequate renal function receiving…
The first hypothesis is that there is variation in the treatment and follow-up of IBD patients between providers and consequently in the outcomes of care. The second hypothesis is that the implementation of a uniform care pathway for the treatment…
We expect positive changes in knowledge, attitudes, and self-reported confidence in knowledge and skills in OHPs who completed TOTIS.
1. Primary: To investigate the effect of internet-based cognitive behavioral therapy (e-CBT) in patients with high levels of preoperative anxiety and/or pain catastrophizing, on the risk of PPBCT six months after breast cancer surgery. e-CBT will be…
We hypothesize that the AI- assessment procedure will have a sensitivity of 98%.
The overall aim of this RCT is to examine whether an individual music intervention can improve the challenging behavior, quality of life, emotional wellbeing and EF of adults with a mild to moderate ID.
We hypothesize that providing feedback to hospitals will reduce practice variation
Patients with ADAM12 > 203 ng/mL in their serum benefit from the addition of biweekly tocilizumab for 3 doses to neoadjuvant chemoradiation before esophagectomy