3499 resultaten
We hypothesize that selfmanagement support via an internet based service in addition to usual care will improve health related quality of life in patients with severe asthma who have participated pulmonary rehabilitation in specialized asthma…
•To assess the safety and tolerability of induction doses of ABP-700 and determine dosing regimens that reliably produce drug induced unconsciousness and the pharmacodynamic conditions necessary for induction of general anesthesia with ABP-700 alone…
To assess in a randomized comparison the effect of Ibrutinib added to 10-day decitabine treatment on the cumulative CR/CRi rate after 3 cycles. To assess the safety and tolerability of Ibrutinib added to 10-day decitabine treatment for AML (…
Chronic heart failure (CHF) is a clinical syndrome resulting from a decreased cardiac output, insufficient to maintain adequate tissue oxygenation. Eventually, inadequate tissue oxygenation will lead to pathological alterations, especially at the…
Teres Major muscle transfer group will show significant better improvement in active abduction and external rotation than the LD group after 1 year.
Intravesical instillation of BCG is a widely accepted strategy to prevent recurrence of non muscle invasive bladder cancer. The most accepted treatment schedule is induction of BCG: weeks 1 through 6 plus maintenance (weeks 1,2,3) at months 3,6 and…
The dentifrice with natural ingredients (Verum) inhibit 10% less gingivitis compared to the placebo dentifrice over a period of 4 months in healthy subjects.
The primary objective of the study is to investigate the role of expectations on conditioned pain modulation (CPM). Based on previous research it is expected that negative outcome expectations, induced by the verbal suggestion that a second painful…
Bipolar devices will minimize the disadvantages of the monopolar device; risk of electrolyte disturbances by using saline irrigation, bleeding and the risk of nervous stimulation
With the program Alcohol Alert we will reduce binge drinking of 16 to 18 year old dutch adolescents, through focusing on motivational factors (eg. attitude, self-efficacy), peer factors (eg. peer pressure, modeling, social norm) and parental factors…
Determine whether fast track perioperative care program is preferred above standard perioperative care program in hand-assisted laparoscopic donornephrectomy.
It is hypothesized that a multifaceted implementation strategy compared to a minimal implementation strategy will be more effective to implement the Participatory Approach (PA) within a company. A tailored training for supervisors in applying the PA…
Minimal invasive fusion results in a longer time spent in satisfactory symptom state (based on the ODI being below 20) than open fusion of the lumbar spine in patients with one- or two-level spinal stenosis and instability, associated with…
Establish the safety and feasibility of sequential chemotherapy and SRT.
A relative reduction of 50% in the occurence of traveller's diarrhoea.
The aim of this study is to characterize the proportion and extent of patients who return-to-work and who enter (partial) disability pension in a “labouring class” of patient infected by COVID-19, who were admitted to the hospital for medium- and/or…
Extension of SAD PK/PD Model, confirmation of SAD PD effects
Good oocyte quality and maturity are important prerequisites for higher fertilization and implantation rates in IVF/ICSI treatment cycles. Reactive oxygen species (ROS) are produced within ovarian follicles, especially during ovulation process, and…