47 resultaten
The aim was to study the effect of apple cider vinegar on the rate of gastric emptying on insulin-dependent diabetes mellitus patients with diabetic gastroparesis.
The hypothesis is that low dose GC therapy exerts its anti-inflammatory effect by virtue of a first-pass effect through the liver. It is difficult to directly address the hypothesis, but there is an indirect way of doing so: if indeed low dose GCs…
4 week n-3 PUFA supplementation will enhance daily muscle protein synthesis rates in older men on a standardized diet.
We expect the number of seizures to decrease with the introduction of a seizure dog. Besides the effect of seizure dogs on seizure frequency, we expect an impact on participation, well-being, health-related quality of life, healthcare resource use (…
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In the process of developing a serious game for testing patients’ level of myocontrol a part of the test needs to be validated. In a previous trial we found differences between several tests that need further inspection. The current study focusses…
We expect that the shape of the cracker influences the amount of cheese consumers will add to their cracker (increase / decrease cheese intake). In addition, we expect that increased cheese viscosity increases oro-sensory exposure time (increased…
Polystyrene sulfonate shows an in-vitro binding interaction with amitriptyline, causing 70-80% binding of amitriptyline to polystyrene sulfonate. The hypothesis is that polystyrene sulfonate binds to amitriptyline when taken simoultaneously in…
The main objective of the FitSupport study is to include 3000 supporters of the soccer clubs into the intervention through two different inclusion strategies; one digital and one personal recruitment strategy. These participants will be divided in…
Warmte zorgt voor toename van de doorbloeding, welke lokaal een afname van de endotheelfunctie na een maaltijd kan voorkomen.
Timing and dosing of BH4 potentially impacts Phe and Tyr variation in PKU patients treated with BH4 and thus potentially impacts outcome.
1. The addition of moderate positive end-expiratory pressure (PEEP, 7.5 cmH2O) to high inspiratory fractions of oxygen can either improve oxygenation or reduce respiratory rate, or both, in patients with severe Covid-19 pneumonia 2. The application…
It was hypothesised that the smartphone-administered eQoR-15NL has comparable measurement properties (i.e. measurement equivalence) compared to the paper-based QoR-15NL questionnaire.
1. High school Freshman develop less positive attitudes towards substance use after participation in Fresh Start than high school freshman in the waitlist control condition. 2. Fresh Start is more effective when it is implemented at the beginning of…
Evaluation of eculizumab treatment in PNH patients at home compared to treatment at the center of excellence in the Netherlands.
1. A meal consisting of harder-textured foods leads to lower energy intake at a lunchtime meal compared to a meal with softer-textured foods; 2. The decreased energy intake of the meal composed of harder-textured foods will not be compensated at the…
To assess the effect of the administration of norepinephrine on ABP while subjects are awake and subsequently, to study the effects of the interactions of norepinephrine and anesthetics (propofol and remifentanil) on ABP under steady-state…