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A self help brochure will help people decrease their excessive worrying. and telephonic support will increase the effect.
The percentage of curatively treatable metastatic disease after surgery for primary colorectal cancer can be increased by means of optimizing follow-up of colorectal carcinoma. Intensifying the follow-up by increasing frequency of CEA measurements…
We hypothesize that the UC Diet (UCD) can improve induction of remission rates when administered with a 5ASA regimen to pediatric patients with mild-moderate UC vs. 5ASA regimen alone.
Hypothesis: arterial oxygen concentrations induce dose-dependent hemodynamic and microcirculatory changes during oxygen supply in mechanically ventilated, post cardiac surgery, ICU patients. Aim: In this study we want to investigate the effects of…
Smart energy meter data used in a monitoring system to alert users when out-of-the-ordinary activity is detected, may improve health-related quality of life and perceived safety of community-dwelling older persons and their informal care providers.
In the current study, we will construct utility functions of two opioids, tapentadol and oxycodone, to assess the benefit/harm ratio of these drugs. To that end we will perform a PK PD study in healthy volunteers
Pain is an unpleasant experience with a multifactorial aetiology. It is feared by most people undergoing surgery. In the postoperative period pain is controlled using many different drugs. All of these drugs have their own adverse events. Ideally…
Amlodipine is prescribed off-label for paediatric patients, but there is no safe, efficacious and appropriate paediatric formulation available. Therefore, an appropriate amlodipine besilate oral liquid 0,5 mg/ml is developed. In order to establish…
We hypothesize that cardiac output rather than blood pressure is essential for adequate cerebral perfusion during and after cerebral revascularization.
The administered protein mix is related to a faster postprandial amino acid bioavailability compared to a single protein as measured by the t½ of the iAUC.
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In this randomised controlled study, the effects of art therapy is examined on psychological functioning of patients with a personality disorder. It is expected that art therapy results in less personality pathology, more acceptance, and less…
I. Test whether psychological and psychophysiological indices of PC are differentially affected by fantasizing vs. mindfulness in remitted MDD patients and HC: Pre-and peri-intervention changes will be examined using within-subject and between-group…
• The amino acid profile of duckweed derived protein may be different from pea derived protein. • The glucose and insulin responses of duckweed protein may be different compared to those of pea protein. • A single intake of duckweed and pea protein…
Inhalation of salbutamol in a forward leaning body posture with the head flexed backwards leads to more reversibility of lung function compared to inhalation with the standard body posture during spirometry in asthmatic children.
Cross-transmission of antibiotic-resistant pathogens can be prevented by using closed suction systems (CSS) instead of open suction systems (OSS) in mechanically ventilated ICU patients.
Neurostimulation can improve collateral perfusion measured as a Pw/Pa ratio, during acute coronary occlusione.
To explore the effect of switching treatment from innovator infliximab (Remicade®) to infliximab biosimilar (Inflectra®, Remsima®) on efficacy, safety and immunogenicity in patients with rheumatoid arthritis (RA), spondyloarthritis (SpA) or…
Whether the bioavailability of ciprofloxacin oral suspension and tablets are equivalent and can therefore be used interchangeably.
Atherosclerosis is characterized by a persistent inflammation of the arterial wall. Monocyte-derived macrophages are the most abundant immune cells in atherosclerotic plaques. It has recently been shown that not only immune cells of the adaptive…