39 resultaten
Phytosphingosine decreases cholesterol levels and improves insulin sensitivity
The efficacy of reflux inhibitors, which block transient lower esophageal sphincter relaxations (TLESRs), to reduce acid and non-acid exposure may be hampered in the presence of a hiatal hernia, as other mechanisms of reflux become more important.
The main objective of this study is to investigate to what extent the acute effects of MDMA on cognitive function, prolactin and cortisol levels, body temperature, heart rate and blood pressure are influenced by co-exposure to THC.
1. At baseline, memory performance and neuroendocrine reactions are expected to differ between novice MDMA (< 10 ecstasy exposures) users and heavy/experienced MDMA users (>100 ecstasy exposures). It is hypothesized that heavy MDMA…
Part 1: Previously, the use of a rollator has been shown to improve functional mobility in patients with COPD. We hypothesize that a new walking aid will result in a larger improvement in 6-minute walking distance as compared to the rollator.…
The exerted pressure on the skin by non-invasive pelvic circumferential compression devices (PCCDs) carries a risk of pressure sores and skin necrosis in case of prolonged use. A persons Body Mass Index (BMI) is of influence on this risk.
We hypothesise that aspirin 100mg at bedtime decreases tension by nocturnally lessening increase of the renin-angiotensin-aldosterone system, enhancing NO bioavailability, lessening autonomous nervous system activity or inhibiting COX-1 dependent…
Showering shortly after application of Androgel does not negatively affect testosterone plasma levels.
Fluoxetine and movement observation are able to increase cortical activity after stroke
Long-chain triglyceride (LCT) emulsions with very small droplet sizes (fine emulsion) will lead to enhanced postprandial satiety and reduced energy intake in a subsequent meal, as compared to LCT emulsions with relatively large droplet sizes (coarse…
We hypothesize that vardenafil improves cognition. This will be apparent as increased recall/recognition scores in a verbal and pictorial memory task, as well as percentage correct in a spatial memory paradigm.
This study is designed to study the contribution and quantification of norketamine for its analgetic and psychomimetic effects
Assuming that the use of SDD would result in an estimated infection prevalence of 25%, a difference larger than 10% was to be excluded, hypothesizing an equivalent efficacy of L. plantarum 299/299V plus fibre compared to that of SDD in preventing…
1. Cannabis use increases striatal dopamine release 2. Striatal dopamine release predicts cannabis induced-psychotic experiences 3. Cannabis-induced striatal dopamine response varies as a function of genetic risk for psychosis
Gravity compensation in addition to intensive exercise therapy will result in a greater improvement in upper extremity function compared to intensive exercise practice without gravity compensation.
Topiramate treatment leads to improvement in Insulin sensitivity independent of weight reduction
To investigate the influence of omeprazole on the metabolism and plasma pharmacokinetics (PK) of irinotecan and its metabolites in cancer patients.
10 grams of a hydrolysate effectively increase insulin secretion and lowers plasma glucose levels after a 25 or 50 grams carbohydrate load in type 2 diabetes mellitus (DM-2)
We hypothesise that increasing the luminal surface exposed to the emulsion will lead to a decrease in hunger and food intake, but that otherwise, the ileal infusion will have the greatest impact on these parameters.