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This present study is a pharmacodynamic study of which the main goal is to confirm the lack of effect of testosterone sublingual alone in 16 premenopausal sexually dysfunctional healthy women using physiological and subjective measures of sexual…
Preoperative planning with x-ray-based PSI have comparable outcome as 3D used MRI-based PSI resulting in indirectly reduced costs on storage of implants and instruments.
Phytosphingosine decreases cholesterol levels and improves insulin sensitivity
Autofluorescence endoscopy (AFE) has a higher sensitivity for the detection of colorectal adenomas in comparison with white light video endoscopy (WLE).
Phenylalanine supplementation can result in higher phenylalanine concentrations without causes tyrosine concentrations to rise too much
The efficacy of reflux inhibitors, which block transient lower esophageal sphincter relaxations (TLESRs), to reduce acid and non-acid exposure may be hampered in the presence of a hiatal hernia, as other mechanisms of reflux become more important.
We hypothesize that exogenous, enterally provided glutamine contributes substantially to the de novo synthesis of arginine in critically ill patients.
Hypersalivation or sialorrhea is one of the most frequently occuring side effects of clozapine use with an incidence ranging from 30 to 90%. In most cases it occurs at the start of clozapine treatment, mostly at night and persists during further…
The hypothesis is that low dose GC therapy exerts its anti-inflammatory effect by virtue of a first-pass effect through the liver. It is difficult to directly address the hypothesis, but there is an indirect way of doing so: if indeed low dose GCs…
Deep brain stimulation of the nucleus accumbens decreases drug use and craving in treatment refractory heroin and/or cocaine dependence.
The aim of this phase I study is to assess the extent of intestinal absorption of rivaroxaban and dabigatran etexilate in adult patients with short bowel syndrome requiring long-term TPN.
It is hypothesized that the behavioral effect (i.e. slower RT and impaired attention) of a non-sedative antihistamine will be apparent in combination with a Pgp-blocker, but will not be apparent when administered alone. This, because when a non-…
Evaluation of difference in tolerability and efficacy as measured by bonemarkers between generic versus brand alendronate in postmenopausal women with osteoporosis.
The behavioural effects of an antihistamine is apparent in the evening after an evening dose, but will be smaller in the morning after a morning dose condition due to the excessive release of histamine shortly after awaking.
Preceding dwell with icodextrin does not influence the results of the 3.86% glucose PET in CAPD.
Co-ingesting keto-analogues of branched-chain AAs along with protein during HD attenuates HD-initiated muscle catabolism.
Administration of a lipid emulsion consisting of long-chain triglycerides (LCT-trial) in non-trained individuals, will induce insulin resistance due to increased DAG accumulation and subsequent activation of the PKC pathway in skeletal muscle.…