142 resultaten
Dietary nitrate supplementation enhances exercise performance of elite athletes competing in intermittent and high-intensity sport disciplines.
A possibly competitive inhibition between imatinib and rosuvastatin as substrates for the same solute carriers (i.e. OATP 1A2 and ABCG2) may result in drug-drug interactions and altered pharmacokinetics of imatinib.
Low field TMS can reduce nociceptive and neuropathic pain.
Allogeneic blood transfusions are reduced when comparing the use of an ABT system to no use of post-operative drains in patients who underwent TKA.
Our hypothesis is that the satiating capacity of protein is partly regulated via the savoury signal of foods. We therefore expect that the savoury diet is more satiating than the sweet diet and the control diet, resulting in a decreased intake after…
To determine the influence of prednisone on docetaxel pharmacokinetics compared to docetaxel alone
Rivastigmine can reverse a memory impairment that is induced by biperiden, which will be seen both behaviorally and in the EEG.
Fentanyl is a strong opioïd and is highly lipophilic. Fentanyl pharmacokinetics are characterised by large inter- and intrapatient differences, which may have serious consequences for the activity and toxicity profile of this drug. The use of…
Based on previous studies, we will expect that ambroxol improves neurological manifestations in patients with GD3.
In line with results from recent pharmacological studies, it is expected that: 1. Inhibiting the cholinergic system by Inversine (Mecamylamine Hydrochloride) results in an impairment of disengagement, but will not affect bias; 2. Inhibiting the…
1. Cysteine is an essential amino acid for newborn preterm infants; 2. Cysteine requirements change rapidly with postnatal age; 3. The change in cysteine requirement with age is based upon cystathionase activity; 4. Intestinal cystathionase activity…
The administration of propranolol will inhibit the increase in dermal blood flow (DBF) induced by capsaicin application.
Suppression of SWS, without changing total sleep time, may affect total energy expenditure (TEE), activity induced energy expenditure (AEE), non-exercise activity thermogenesis (NEAT), endocrinological parameters and energy intake.
1. Active sniffing decreases appetite; 2. Food choice is mainly influenced by the food odour that was perceived first.
The objective is to identify a formulation of ModraCape001 that will release capecitabine in vivo over a time-period of about 18 hours. We hypothesize that prolonged exposure, without a high peak exposure to capecitabine, improves the benefit/risk…
This study was therefore designed to determine whether cinnamon lower postprandial blood glucose, and insulin levels in subjects with type 2 diabetes or impaired glucose tolerance.
We hypothesize that consumption of mixtures of 400 grams vegetables and/or fruits for 2 weeks will result in lower ex-vivo induced oxidative DNA damage, increased antioxidant capacity of blood plasma, reduced levels of reactive oxygen species in…
Appropriate use and prescription of a lower limb prosthesis for people with leg amputation through or above the knee, can increase the efficiency of the integrated care around the leg prosthesis.
A four day adminstration of N-acetylcysteine (3600 mg/day) will reduce craving, withdrawal symptoms and the bias towards nicotine related cues compared to a four day administration of placebo in nicotine dependent subjects.
We hypothesized that FFA loading could impair mitochondrial function and that the potency of FFA to disturb mitochondrial function and glucose uptake would depend on the degree of desaturation of the fatty acids infused.