27 resultaten
1. DKD patients are salt-sensitive due to a decreased sodium buffering capacity (damaged ESL). As a consequence a high sodium diet will lead to water retention, resulting in increased ECF, body weight and blood pressure. 2. CKD patients are salt-…
Our hypothesis is that contratile segment impedance is a marker for EoE-disease activity (histological remission or active disease)
Main hypothesis The BENEFIT intervention will significantly increase the number of CVD patients that can maintain the healthy lifestyle behavior most relevant to them for at least one year, compared to care-as-usual. Secondary hypothesis The BENEFIT…
We hypothesize that the metabolic effects of acute infusion of acetate are different in insulin resistant subjects compared to lean subjects.
Which design of cognitive aid (emergency manual) is easier to use and results in less missed critical actions during anesthetic emergencies
Better glucose control during the closed loop system compared to standard open loop therapy
A nursing nutrition intervention improves protein and energy intake and performance based on hand grip strength compared to usual care.
We hypothesize that methylphenidate improves ADHD manifestations in children and adults with SMS.
We hypothesize that the MMP could be cost-efficient for a part of the patients, but that for some patients a more simple prosthesis would be more cost-efficient. Therefore, we do not expect big differences in cost-effectiveness between the MMP and…
We hypothesize that E171 induces gene expression changes in the colon that explain the inflammatory mechanism of E171 in the colon, which facilitate the development of colorectal cancer. In addition, inflammatory markers will be increased in the…
Golimumab 100 mg every 1,5 month has similar trough levels to golimumab 50 mg every month; golimumab 100 mg every 2 months has a similar AUC to golimumab 50 mg every month.
A 4-month WFPD H0: has no effect on the levels of serum uric acid in patients with gout, hyperuricemia and abdominal obesity in comparison with usual care. H1: results in decreased levels of serum uric acid in patients with gout, hyperuricemia and…
We hypothesize that consumption of mixtures of 400 grams vegetables and/or fruits for 2 weeks will result in lower ex-vivo induced oxidative DNA damage, increased antioxidant capacity of blood plasma, reduced levels of reactive oxygen species in…
We hypothesize that the use of KomPas at the start and during the SET will be associated with increased functional walking distance, maximal walking distance and the quality of life of patients with Intermittent Claudication. Moreover, we…
To test the hypothesis that apathy after STN DBS may be reversed by switching the activated contact on the DBS-electrode from a ventral to a more dorsal contact.
• Overall, the patient-tailored PROfeel lifestyle advice will be more effective in reducing patients’ fatigue severity than the generic dietary advice. • Overall, the patient-tailored PROfeel lifestyle advice will have a more positive effect on…
Primary hypothesis is whether patients with a PTSD the distraction of a positive emotional valence will be more effective in decreasing the vividness and emotionality of a traumatic memory compared to distraction with a neutral task or exposure only…
2C-B generates distinct acute and subacute effects from Psilocybin and placebo
The hypothesis of this study is that implementation of an evidence-based management algorithm to standardize care will improve the level of care, lower the complication rate and improve the quality of life for patients with chronic pancreatitis.
We hypothesize that giving feedback to healthcare providers on the performance of their own hospital improves processes of care and leads to better outcomes.