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We hypothesize that PHA-022121 will be more effective in both the treatment and prophylaxis of acute angioedema attacks in patients with acquired C1-inhibitor deficiency when compared to placebo.
Based on previous studies, we will expect that ambroxol improves neurological manifestations in patients with GD3.
Timing and dosing of BH4 potentially impacts Phe and Tyr variation in PKU patients treated with BH4 and thus potentially impacts outcome.
We hypothesize that the ceftriaxone monotherapy strategy is non-inferior for mortality and for nephrotoxicity a strategy of ceftriaxone monotherapy is superior to a strategy of cefuroxime combined with short course aminoglycosides.
It was hypothesised that the smartphone-administered eQoR-15NL has comparable measurement properties (i.e. measurement equivalence) compared to the paper-based QoR-15NL questionnaire.
As the pain quality item “unpleasantness” delineates EB pain, we hypothesize the modulation of affective pain processing in the brain by way of intervention with Transvamix (a CBM comprising THC and CBD) - objectified by functional magnetic…
To assess the effect of the administration of norepinephrine on ABP while subjects are awake and subsequently, to study the effects of the interactions of norepinephrine and anesthetics (propofol and remifentanil) on ABP under steady-state…
Significantly more patients will express an overall preference for ICI-P versus ICI-B