132 resultaten
This study aims to investigate the value and feasibility of a disposable TEE to monitor both fluid responsiveness and global contractile function of both left and right ventricles in high risk surgical patients, including both intraoperative…
The primary aim of the study is to investigate whether it is possible to select patients by PET in a good prognosis group (i.e. low SUV) who will not benefit from adjuvant chemotherapy.
Certain patient-specific factors contribute significantly to the outcome of delivery after a cesarean section in a Dutch hospital setting. These factors influence the decision to initiate trial of labour (TOL) or plan for an elective repeat…
We hypothesize that, in line with the results of the previous study, cheilectomy and Keller’s arthroplasty show better clinical and subjective outcome in patients treated for low grade HR compared to arthrodesis. In addition, we hypothesize that…
1. Curative treatment of primary metastasized rectal cancer includes resection of primary tumor and metastases; 2. Primary tumors in case of metastasized disease are often locally advanced and need downsizing before resection; 3. Systemic treatment…
Sound/salient support of treatment recommendations with argumentations will enhance parental recall/agreement/acceptance of these recommendations and enhance their perceptions of the pediatrician/neonatologist as a credible and patient centered…
Can imaging surveillance frequency be safely reduced in a select group of EVAR patients, i.e. patients with an asymptomatic infrarenal abdominal aortic aneurysm (AAA) that underwent EVAR without abnormalities on the initial postoperative CTA.
1. Flat adenomas are common findings in patients at average- or at high-risk for CRC; 2. Flat adenomas are characterized by a different molecular profile as compared to polypoid lesions; these molecular features are associated with an increased risk…
The use of ECLS can lead to systemic inflammatory response. It is likely that ECLS affects red blood cell and platelet function after its initiation, the time course of these changes and their clinical relevance is yet unclear.
The aims of the present study are: 1. To give a comprehensive description of 200 adults (> 18 yr) with recently diagnosed adult-onset asthma (< 1 yr); 2. To define clinical, lung function or inflammatory or mixed phenotypes of adult…
If subjects view a video a medical consultation, then viewing physician-patient commmunication will yield similar psychological and physiological responses as when that subject is taking part in that consultation.
The aim of this study is to provide more insight in the therapeutic effect and mechanism of action of intramyocardial bone marrow cell injection in patients with refractionary angina pectoris and documented ischemia.
Children who play the serious game that stimulate health behaviour show healthier eating behaviour than children who do not play the serious game.
Aims: 1. To describe the prevalence and incidence of difficult-to-treat adult asthma in the Netherlands; 2. To describe factors associated with adherence with pulmonary medication in patients with difficult-to-treat airway disease; 3. To score the…
The current study evaluates whether accurate optical diagnosis of small colorectal polyps (<10mm) in vivo in a non-expert setting can be achieved, resulting in the omission of formal histopathology, which could make colonoscopy more efficient…
The primary goal is to show the capability of monocyte-derived DC after RNA electroporation for multiple antigens to induce an immune response. The secondary objective is to show clinical response.
When the optimal MRI protocol for imaging the sacral plexus and its branching nerves is known, the sacral plexus of children having neurogenic bladder dysfunction due to congenital spinal or sacral anomalies can be imaged. Because not much is known…
To prospectively assess the efficacy, feasibility and safety of a systemised endoscopic surveillance protocol in large multicentre HPS cohort.
To determine the sensitivity and specificity and positive and negetive predictive value of MRI in a consecutive series of pediatric patients suspected for acute appendicitis.
There is no reliable biological marker for the diagnosis of Acute Mountain Sickness (AMS), so AMS is presently assessed with questionnaires: the Lake Louise self-report score (LLSRS) and the abbreviated Environmental Symptoms Questionnaire (ESQc).…