14 resultaten
1. What are characteristic (neuro)physiological factors of fatigue in disease-free cancer patients? 2. To which degree can these factors be influenced by Cognitive Behavior Therapy?
Approximately 2% of the Dutch elderly population suffers from a major depressive disorder (MDD). Due to a depressed mood and a diminished interest in nearly all activities, MDD has serious consequences for daily living (e.g. withdrawal from social…
Short-term cognitive behavioral therapy (CBT) given by primary health care workers with patients with chronic benzodiazepine use and new patients in the family practice with sleepinsdisorder, hypothised that CBT results in reduction of…
1. In Barrett Esophagus (BE), probe-based laser endomicroscopy (pCLE) provides better correlation with the histological diagnosis compared to detailed inspection with Narrow Band Imaging (NBI), reducing the high rate of false-positive findings with…
Het is veilig en haalbaar om in 1-2 gastroscopieen zowel een BDstent te plaatsen als brachytherapie toe te dienen.
It can be hypothesized that fast track care and/or laparoscopy are associated with less exaggerated inflammatory response during and after surgery resulting in faster recovery of postoperative gastrointestinal motility.
NAVA (neurally adjusted ventilatory assist) is a newform of artificial respiration, based on the electrical activity of the diafragma. We want to investigate wether there are fysiological differences between the conventional mode and NAVA.
1. Curative treatment of primary metastasized rectal cancer includes resection of primary tumor and metastases; 2. Primary tumors in case of metastasized disease are often locally advanced and need downsizing before resection; 3. Systemic treatment…
The aim of this study is to develop and evaluate a patient-oriented treatment decision aid (PTDA) focussing on shared goal-setting and decision making, which is tailored to the needs and capacities of a heterogeneous group of patients with type 2…
1. Flat adenomas are common findings in patients at average- or at high-risk for CRC; 2. Flat adenomas are characterized by a different molecular profile as compared to polypoid lesions; these molecular features are associated with an increased risk…
The aims of the present study are: 1. To give a comprehensive description of 200 adults (> 18 yr) with recently diagnosed adult-onset asthma (< 1 yr); 2. To define clinical, lung function or inflammatory or mixed phenotypes of adult…
To determine the sensitivity and specificity and positive and negetive predictive value of MRI in a consecutive series of pediatric patients suspected for acute appendicitis.
Phenotyping of patients with adult onset asthma by linking clinical, functional and molecular markers will: 1. Reveal distinct risk factors of severity and poor quality of life; 2. Provide evidence that recent onset asthma in adulthood is relatively…
1. TGC with insulin in continuous tube fed patients is superior to TGC with insulin in regularly fed patients; 2. Vildagliptin as add-on therapy to insulin mediated TGC results in less hypoglycemic episodes compared to placebo.