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Hard-core smokers are smokers who have been smoking for many years and who do not intend to quit. This makes them vulnerable to disease and death. Since hard-core smokers are unlikely to quit smoking, before aiming at actually quitting, we first…
Sunitinib, when given in a high-dose, intermittent schedule, may exhibit improved efficacy with an acceptable toxicity profile.
Bipolar radiofrequency lesioning of the thoracic medial branch of the dorsal ramus is more effective than a monopolar radiofrequency lesion
The temporal artery biopsy has no additional value after a halo sign using ultrasound of the temporal artery
HIV-infection and antiretroviral therapy use may lead to a diminished neurological and neurocognitive performance in HIV-infected children.
Age associated molecullar processess are involved in rotator cuff degeneration and the presence of rotator cuff tears
medication reconciliation by pharmacists decreases the amount of medication transfer errors in patients admitted to the intensive care
The implicit training (AAT) added to standard behaviour therapy will reduce relapse rates after treatment when compared to the control group.
We hypothesize that age-related changes in hepatic and intestinal drug metabolism affect the pharmacokinetics of paracetamol.
We expect that when the developed checklist will be used in de diagnostic proces of children with developmental and/or behavioral disability, the use of pediatric care will be more efficiently used. Over and underdiagnoses of a causal somatic…
Information on the dynamics and shape of the device and how these change over time will improve our understanding about the fixation and/or sealing of the device, which may help in stent selection and in designing stent grafts that are more durable.
The overall goal of this study is to test if the analogue patient paradigm is a valid method to assess the effects of physician-patient communication. More specifically, in Phase I, we aim to test if viewing a role-played interview about a common…
The carotid artery reactivity-test will have independent prognostic value compared to the current, standard prognostic tests (i.e. ankle-brachial-index, walking distance) for patients with peripheral artery disease
The efficacy of transluminal drainage of pancreatic fluid collections may be increased by creation of a larger fistula than currently possible with placement of multiple plastic endoprostheses.
Whole Body Vibration (WBV) applied via a chair has positive chronic effects on cognitive function of older people.
The aim of the study is the assessment of microcirculatory alterations induced by xenon or sevoflurane anesthesia in patients with compromised left ventricular systolic function.
Liver and adipose tissue levels as well as serum levels of RBP4 are higher in obese subjects compared to lean subjects. In obese subjects tissue and serum levels of RPB4 are correlated with insulin sensitivity and hepatic triglyceride content.
It is expected that, for each of the three CBM paradigms, participants in the intervention conditions will show a greater decrease in weekly alcohol use than participants in the control conditions. Generalization of each specific CBM paradigm to…
A 10% point difference between the experimental and control group in HPV-vaccination uptake is expected. Assuming 58% of participants daughters in the control group receive two HPV-injections and a 10% point difference between the experimental and…