42 resultaten
Opening wedge HTO treated with DBM will better match one year post-operative mechanical axis alignement with pre-operative planned correction then opening wedeg HTO filled with autogenous iliac crest bone.
Recently, (changes in) the gut microbiome (flora / bacteria) have been associated with obesity and insulin resistance, and other cardiovascular risk factors or atherogenic processes. Venous thrombosis shares these risk factors, probably by a shared…
1. The recognition of malnourished inpatients will improve by using the SNAQ malnutrition screening tool at admission; 2. Early recognition and treatment of malnutrition is effective and cost effective.
We hypothesise that CAP is a safe treatment that reduces bacterial load on the wound surface and promotes wound healing.
We believe that a routine graft biopsy at 6 and 12 months together with graft function represents the best surrogate marker for late graft loss.
The goal of this study is: 1. To offer a uniform, standardized concept for the treatment of children and adolescents affected by low grade glioma; 2. To improve progression free survival following non-surgical therapy for children without NFI with…
To assess the change in arterial wall inflammation, measured with 18F-FDG PET/CT, in patients with increased CV-risk and statin intolerance due to statin-associated muscle symptoms after PCSK9 inhibition
A SPT has been proposed to screen subjects with increased risk of hypersensitivity reaction to Ruconest. Subjects with RA and subjects with clinical CMA have an increased risk of hypersensitivity: although cow's milk proteins differ from rabbit…
We hypothesize that age-related changes in hepatic and intestinal drug metabolism affect the pharmacokinetics of paracetamol.
Type 2 diabetes is cause by progressive beta-cell dysfunction against a background of obesity and insulin resistance in susceptible individuals. Peroxisome proliferator-activated receptor (PPAR) gamma-mediated mechanisms are involved in the…
Develop a screening tool to identify children at risk of posttraumatic stress disorder after an accident.
NAVA (neurally adjusted ventilatory assist) is a newform of artificial respiration, based on the electrical activity of the diafragma. We want to investigate wether there are fysiological differences between the conventional mode and NAVA.
Evaluation of efficacy and safety of two different formulas of alfa-Galactosidase A, agalsidase beta (FabrazymeTM) and agalsidase alpha (ReplagalTM) in an equal dose of 0,2 mg/kg in order to detect any differences between these two drugs.
Botulinum toxin A declines the severity of tardive dyskinisias.
Comparison of two new techniques for detection of small bowel pathology: MR enteroclysis and videocapsule enteroscopy with double-balloon enteroscopy with respect to diagnostic yield, accuracy of findings, and patient preference.
For patients with breast cancer who are not applicable for breast-saving treatment (because of tumor characteristics), who prefer an amputation or who undergo a prophylactic amputation an immediate breast reconstruction is a standard offer. A…
Our hypothesis is that the iron status in young healthy children from the Netherlands might be insufficient.
The present study is a feasibility study. In this study we will test the feasibility of the procedures used, the compliance to the interventions, and the usefulness of intermediate outcome measures in a specific high risk group. If the results of…
The aim of the current study is to test whether online training of a positive attentional bias and/or working memory capacity can reduce anxiety and/or depressive symptoms in adults with heightened emotional symptoms.