26 resultaten
The aim of the study is to gather information regarding COVID-19 infections during pregnancy. Up to now, little is known about COVID-19 during pregnancy.
The main clinical challenge remains to identify patients who may benefit from aggressive local treatment (stereotactic radiotherapy, SBRT) of soft tissue oligometastases: for which patients can systemic treatment be postponed? Patients who are…
The gastric balloons are expected to remain in the stomach for approximately four weeks, after which they burst and are fecally excreted. It is further hypothesised that intragastric balloons can provide a surrogate stomach fill, inducing an…
Simvastatin (an HMG-CoA reductase inhibitor) induces apoptosis in vitro and sensitizes the myeloma cell to chemotherapy. This is the first clinical trial to test if in vivo there is the same sensitization in relapse or refractory multiple myeloma.
to further evaluate and monitor the safety and performance of the “BasIQ-4®” in a population of women delivering in general hospitals in The Netherlands when used as intended
Conditions during an IVF procedure might interfere with fetal growth and development and thereby permanently influencing the programming of organs and their function.
To evaluate the effects of thoracic epidural anaesthesia (TEA) with general anaesthesia on mean systemic filling pressures, arterial- and venous resistance and cardiac output. To assess the hemodynamic effects of vasopressors and fluid loading under…
As EGFR plays a role in pathogenesis of both pulmonary arterial hypertension and systemic sclerosis, EGFR inhibition will lead to beneficial effects in disease course.
The aim of this study is to assess the predictive value of the HowRwe questionnaire in relation to the EUROPEP questionnaire by analyzing scores acquired in Dutch GP practices. We expect that high HowRwe scores are associated with an positive…
The primary hypothesis of this study is that Opsys will improve mild incontinence based on urine loss per 24 h measured by 24 h pad weight test (PWT). Primary Objective The primary objective of this study is to test the effectiveness of Opsys in a…
We hypothesize that FMT from a healthy donor will modulate the microbiome of the pouch of patients with ulcerative colitis, and will thereby resolve the inflammation of the pouch.
It is hypothesized that the FitMáx© questionnaire is a valid clinical assessment tool for CRF compared to the gold standard, a cardiopulmonary exercise test. Moreover we believe the FitMáx© to be fairly accurate in the preoperative risk assessment…
A disease control of 60% is expected and will be clinically relevant with a lower reference bound of 45%.
SARS-CoV-2 is present in the cerebrospinal fluid of COVID-19 patients with acute respiratory failure
Because the aim of this observational study is to obtain insight in the nutrient and fluid intake, and nutrient and biomarker concentrations in the blood in patients with ischemic stroke, the focus will be on descriptive statistics and there will be…
It was hypothesized that comparing the course of uveitis of individual eyes with respect to inflammatory activity and visual acuity (VA), and the impact of particular therapies, to already available data about course and outcome from other patients…
The aim of this study is to assess whether the use of the IncoSense Smart leads to improvement in efficiency of incontinence care, better quality of life of the clients and reduction of the cost.
We hypothesize that chemotherapy-induced changes in exhaled metabolites in lung cancer can be detected by changes in VOC profiles (smell-prints) measured by the eNose.
We hypothesize that an electronic nose can discriminate the VOC pattern in exhaled breath between patients with non small cell lung cancer (NSCLC) and breast cancer.