1222 resultaten
It is expected that the urinary and serum level of intestinal fatty acid binding protein (I-FABP) and the urinary level of Claudin-3 have prognostic relevance for early identification of patients at risk for intestinal ischemia-related morbidity or…
to improve the medical care on long term follow up
The main clinical challenge remains to identify patients who may benefit from aggressive local treatment (stereotactic radiotherapy, SBRT) of soft tissue oligometastases: for which patients can systemic treatment be postponed? Patients who are…
To evaluate the incidence, risk factors and perinatal morbidity and mortality due to CA after TTTS treated with fetoscopic laser surgery
Gut dysbiosis drives disease processes driving morbidity and mortality in acute pancreatitis, such as infected pancreatic necrosis, and (persistent) multiple organ failure. A decrease in commensal members of the bacterial microbiome allows for…
Prevalence of PNH in selection of patients with DVT. Patients younger than 30 years of age. patients with DVT on unusual places.
Part 1: Primary: Patients who are more susceptible to nocebo effects at baseline will have greater clinical pain progression from baseline to one-year follow-up. Secondary 1: Patients who are more resilient to extinction will have greater clinical…
About 25% of patients who suffer from a subarachnoid hemorrhage or intraventricular hemorrhage have a vital indication for an external ventricular or lumbar drain to aleviate the intracranial pressure. About 5-10% of these patients develop a…
Patients could be stratified into a high-risk or a low-risk group so surveillance intervals can be tailored and the clinical and economic burden of endoscopic surveillance can be reduced.
AIM: Establish the clinical value of sentinel node biopsy in patients with multiple breast tumors. Investigate if an intratumoral tracer injection in the additional tumors results in visualization of extra sentinel nodes/extra lymphatic drainage…
There is considerable interlaboratory variation in the grading of dysplasia in duodenal adenomas.
1. A higher resting and funtional PFM activity is observed in more distal areas from the introitus of the vagina. 2. A higher resting and funtional PFM activity is observed on the anterior wall of the vagina
The age-specific seroprevalence of a cross-section of the Dutch population for the vaccinations used in the Dutch National Immunisation Programme.
We hypothesize that patients with symptoms of inability to belch have ineffective UES relaxation in response to esophageal distention caused by air.
- Hypothesis#1 efficacy We hypothesize that a quick onset, and a predictable dose-response, good adjustability of analgesia can be achieved with inhaled ketamine. Hypothesis#2 safety Inhalation of nebulized ketamine might lead to a fast onset of…
It is expected that the dynamic version of the Wisconsin Card Sorting Test (dWCST) is a valid measure of cognitive learning potential in terms of psychometric properties and construct validity. In terms of feasibility it is anticipated that the…
We hypothesize that lower renal region or cerebral NIRS values are correlated with a higher incidence of postoperative AKI in this study population
Primary Objective: The main study parameter is to establish the safety of the use of IXSI in an interventional setting. Safety will be assessed based on the CTCAE methodology. Use of IXSI will be considered safe in the absence of Adverse Device…
We hypothesize that frailty in older individuals might underly low responses to the 23-valent polysaccharide pneumococcal vaccination (PPV23) that will be implemented in the National immunization program in autumn this year for elderly 73-79 years…
Data on these complications vary. Since this is an observational study, we are interested in overall incidence and prevalence. Therefore we do not have a clear hypothesis.