369 resultaten
- Hypothesis#1 efficacy We hypothesize that a quick onset, and a predictable dose-response, good adjustability of analgesia can be achieved with inhaled ketamine. Hypothesis#2 safety Inhalation of nebulized ketamine might lead to a fast onset of…
Our hypothesis is that high-dose, pulsatile sorafenib may exhibit improved efficacy with an acceptable toxicity profile compared to standard continuous dosing. AUC escalation cohorts are used instead of the conventional dose escalation cohorts,…
The null-hypothesis predicts that Inlife is not feasible. The alternative hypothesis predicts that the Inlife intervention is evaluated as being feasible. We expect the alternative hypothesis to be true. Inlife will be feasible and minor revisions…
The EuraHS-QoL questionnaire is a valid instrument to measure quality-of-life before and after ventral hernia repair.
Health outcomes for people at risk of or suffering from non-communicable lung diseases in low-resource settings will be improved by developing capacity for implementation of evidence-based interventions for prevention, diagnosis and treatment in…
First, non-invasive diagnostic tools can optimize the diagnostic strategy, in order to minimize the number of invasive diagnostic procedures. Second, invasive imaging of the pulmonary artery can further differentiate the mechanisms involved in PH…
The aim of the study is to develop a screening tool to identify young children at risk of posttraumatic stress disorder following an accident.
We hypothesize that the deformation-area curves will show an alteration in the relationship between deformation and area for the differing (pressure or volume related) cardiovascular diseases
Rationale: Hypertension is the most common cardiovascular condition responsible for the development and maintenance of atrial fibrillation (AF). Treating drug-resistant hypertension with renal denervation has been reported to control blood pressure…
This evaluation does not have a hypothesis to be tested since it is intended to evaluate the workflow and usability of the new software solution, without prior defined performance criteria.
The hypothesis is that a graded physical exercise program in which strength and endurance are trained have a positive effect on fatigue after stroke measured with the CIS-f (Checklist Individual Strength subscale fatigue) or FSS-7 (Fatigue Severity…
Patients suffering from high risk or relapsed leukaemia or high risk MDS can only occasionally be cured with conventional chemotherapy. Allogeneic stem cell transplantation (allo-SCT) has substantially improved the outcome of such patients due to a…
Dupuytren's disease is a progressive disease and often recurs. We will measure increase in degrees of extension deficit 3 and 6 years after treatment with CCH.
The central hypothesis of our study is that routine postsurgical anesthesia visits reduces postoperative 30-day mortality by 30%.
1) Personalized lifestyle advices are an effective way to reduce loss of pleasure in young individuals 2) Exposure to a tandem skydive experience fosters the recommended lifestyle changes that can restore the ability to experience pleasure
The Aeonose is capable to correctly distinguish patients with dyspnea resulting from heart failure from patients with dyspnea caused by lung failure.
The aim of the study is to explore the relation between frailty, functional status and other patient characteristics and adverse outcomes as functional decline, length of stay, admissions and mortality. Frailty is multifactorial and is known to be…
A bundle of inexpensive interventions can reduce the emergence and spread of carbapenem non-susceptible Gram-negative bacteria in a low-resource ICU.
A behavioural intervention will improve hand hygiene baviour and prevent the transmission of hand foot mouth disease