101 resultaten
We hypothesize that by using different imaging techniques, we can give a good characterization of the bone marrow microenvironment in advanced-stage myelofibrosis, before and during treatment with ruxolitinib.
There seems to be a biphasic process of bone mineral density (BMD) changes in osetoarthritis (OA). An increased bone mineral density (BMD) and a specific distribution of BMD in the cortical of the subchondral plates and below in the trabecular bone…
To analyse the diagnostic and prognostic value of plasma EV protein/miRNA and gene expression profiles of circulating cells for objectified ischemic coronary artery disease in patients with symptoms (e.g. chest pain) suggestive of coronary artery…
What are the motivations of women in the Netherlands to choose UC and what are their beliefs on childbirth in general and in relation to current Dutch maternity care? This study primarily aims at understanding women’s motivations in declining (parts…
The rationale for this study is to assess the visibility and positional accuracy of the laser marks. Combined with VLE imagery, the targeting enabled by the laser marking system could have the potential to increase the diagnostic accuracy of current…
Differences in the healthcare, workplace, legislative, and personal systems (see figure) as well as evaluator and patient characteristics may better explain differences in FCE results
We hypothesise that accurate treatment of GOLD D patients in an integrated primary care system will improve patient outcomes over 12 months.
PolyEthylene Glycol with ascorbic acid (PEG-asc) bowel cleansing preparation could contribute to the development of low potassium values. Hypokalemia is partially a pre-existing matter before bowel cleansing. Elderly are at risk for development of…
Radium-223 is the 5th treatment for metastasized castration resistant prostate cancer with a proven overall survival benefit. The improved survival of Radium-223 over placebo was demonstrated in the ALSYMPCA trial, which included a miscellaneous…
Visceral obesity and sarcopenia are associated with increased risk of postoperative complications in colorectal cancer surgery.
Betere patientveiligheidscultuur leidt tot een betere naleving van de richtlijnen op de OK om postoperatieve wondinfecties te voorkomen.
This study is designed to evaluate the effectiveness and safety of the ApiFix (MID-C) System.
Diabetes Mellitus type 1 is an autoimmune disease that cannot be cured. Complications due to insufficient regulation of blood glucose by exogenous insulin reduce life expectancy and quality of life. Proinsuline-loaded Tolerogenic DCs are induce…
We expect that mp-MRI, molecular urine test and Prostate Cancer Risk Calculator may be of additional value in differentiating between significant and insignificant cancers in men with an elevated PSA in the primairy diagnosis. If so, it will result…
Physcial therapy is an effective treatment for patients with hip impingement
To investigate in an unselected memory clinic sample, the clinical value of 18F]FBB PET in terms of 1. change in diagnosis; 2. change in level of confidence of diagnosis; 3. impact on patient healthcare management.
Children with underlying medical conditions, prematurity and low birth weight are at increased risk of hospitalizations due to rotavirus (RV) gastroenteritis, RV related complications and mortality. In a recent Dutch study it was demonstrated that…
The aim of this observational study is to investigate the relationship between orthostatic hypotension and the rate of successful rehabilitation. A previous study showed that orthostatic hypotension increased the risk for successful rehabilitation,…
Patients with diffuse large B cell lymphoma (DLBCL) and with B-cell lymphomas, unclassifiable with features intermediate between diffuse large B cell lymphoma and Burkitt lymphoma (BCL-U) that harbor a MYC rearrangement (MYC+ DLBCL) have a dismal…