261 resultaten
The hypothesis is that twins discordant for pregnancy complications display a distinct epigenetic signature in MSCs. This signature contributes to cellular metabolic alterations and is associated with future cardiovascular and neurodevelopmental…
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The goal of the proposed study is to test the null hypothesis that vaccination will not boost the cytotoxic T cell responses against UTA2-1 in >20% of the patients.
PPI administration to women with confirmed PE lowers sFlt-1 levels and which may lead to less complications or progression of disease.
Based on recent data derived from animal research in combination with earlier clinical trials, we hypothesize that stimulation of cerebellar nuclei in pediatric refractory epilepsy patients might be effective in significantly decreasing epileptic…
1. Post-migration stressors are associated with parental self-efficacy controlling for war-trauma 2. Parents feel more efficacious on days with less post-migration stressors and vice-versa 3. Real Tailored Verbal feedback on parenting will improve…
Switching to sarilumab in patients with rehumatoid arthritis responding well to tocilizumab does not lead to a relevant increase in disease activity and is feasible with a persistence of sarilumab >70% at 6 months
Patients in the intervention group are more physically actice during and the 2nd week after hospitalisation.
This trial aimes to identify patient characteristics which can lead to predictors of succes for technique learning.
The response on medical treatment for moderate to severe ulcerative colitis is visible on intestinal ultrasound within the first 6 weeks according to endoscopic response at 8-26 weeks
There is a significant association between the four basic biomechanical components (size, span width, joint rigidity and strength) and the development of musculoskeletal complaints in string musicians.
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VTE risk prediction might be improved by using the modified risk scores.
We hypothesize that muscle protein breakdown (i.e. amino acid release) is related to increased glutamine utilization by immune cells, gluconeogenesis and synthesis of acute phase proteins.
Remifentanil PCA 20 micrograms is an effective dose for pain relief in labour.
- It is possible to distinguish PD patients from HC based on a combination of ultra-high field MRI characteristics and Quantitative Susceptibility Maps (QSM). - Different PD symptoms are caused by specific changes in different micro-circuits of the…
This study aims to increase the implementation of smoking cessation group trainings with financial incentives among Dutch companies by developing an implementation strategy that will be tested, evaluated and adapted multiple times. We hypothesize…
Daily use of pre-thickened oral nutritional supplements for 12 weeks will have a positive effect on body weight of older nursing home residents with dysphagia and malnutrition (risk) as compared to standard nutritional - and dysphagia management
The primary objective is to prospectively identify cardiac damage in childhood cancer patients, during and shortly after treatment with anthracyclines.