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In patient with clinically suspected appendicitis, imaging is needed to substantiate the clinical diagnosis. Imaging accuracy of US and CT is suboptimal, and the associated use of ionizing radiation and iodinated contrast medium are major drawbacks…
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By using a proactive approach (prompts) compared to a reactive approach CT (computer tailored) program use will be increased by 20 %.
Nadroparine and fondaparinux are both effective in preventing a thromboembolic event in patients with a nonsurgical fracture of a lower extremity immobilised in a below-knee plaster cast.
The aim of the study is to determine whether cardiac output measurements obtained using APCO are comparable with those obtained using intermitted thermodilution cardiac output in critical ill patients.
This is a dose-escalation study to determine the safe dose of clofarabine given in combination with cytarabine and liposomal daunorubicin.
The COL3A1 polymorphism is a inheritable genetic defect, responsible for the increased susceptibility to pelvic organ prolapse in women.
We hypothesize that exercise training improves maximal exercise capacity in adult patients with a systemic RV. Moreover, we hypothesize that exercise training decreases serum NT-proBNP levels and increases quality of life in adult patients with a…
By detection of disease specific deviations in emotion processing in unipolar vs bipolar patients, affective neuropsychological tests and fMRI could be used to discriminate between both affective disorders.
We expect a decrease in the expected satiating capacity of the test food after repeated exposure to the low-energy-dense version of the soup and an increase in expected satiation after the repeated consumption of the high-energy-dense soup.
We hypothise that women with a history of preeclampsia have accelerated vascular aging in comparison with control women with uncomplicated pregnancies.
Better guided resection of brain areas that are, regarding network characteristics, important for seizure onset and propagation may result in improved clinical outcome. However, before such guidance is possible, more insight into the effects of…
To quantify the amount of local anaesthetic in blood and tissue fluid in the Bellovac ABT system and in the blood circulation of the patient. The primary objective is to quantify the cumulative ropivacaine level when the blood should be retransfused…
Prevention of the progression of TMD to ML-DS by chemotherapeutical profylaxis can be possible.
Our primary hypothesis states that cognitive behavioral therapy will improve quality of life and amend illness cognitions and attitudes in IBD patients. Our secondary hypothesis states that improvements in quality of life are mediated by changes in…
Primary objective: To test whether mucosal oxygen saturation has added value to endoscopy and histological examination. Secondary objectives: 1. To test whether detection of hypoxia dependent molecular changes in the mucosa can be used to improve…
Does lipid accumulation in skeletal muscle and the heart effect mitochondrial function in relation to insulin resistance?
We will study which factors differ between the responders to oxygen therapy and the non-responders. Factors that will be studied are for instance patient characteristics, headache characterisics, comorbidities and intoxications.
To assess whether children with relapsed/refractory AML, who do not achieve remission or relapse after treatment with the Relapsed AML 2001/01 standard reinduction protocol (fludarabine, cytarabine and GCSF with or without DaunoXome�), can be…
The purpose of this study is to develop a brief and child-friendly trauma screening instrument to identify children with PTSD and other trauma related symptoms.