819 resultaten
In vulvar cancer patients with a macrometastasis in the sentinel lymph nodes, chemoradiation is as effective as an inguinofemoral lymphadenectomy, but is associated with less treatment-related morbidity.
The hypothesis of this study is that segmental kyphosis can be maintained after removal of the short-segment pedicle-screw instrumentation in biological young patients with traumatic thoracolumbar burst fractures. In these patients in addition to…
Fentanyl is a strong opioïd and is highly lipophilic. Fentanyl pharmacokinetics are characterised by large inter- and intrapatient differences, which may have serious consequences for the activity and toxicity profile of this drug. The use of…
We hypothesized that patients admitted to the hospital during this pandemic period with a suspected or confirmed SARS-CoV2 infection, have a high risk to develop long-term or persistent symptoms of PTSD, anxiety and depression, which are associated…
SARS-CoV-2 is present in the cerebrospinal fluid of COVID-19 patients with acute respiratory failure
We hypoothesize that the effect that a single dose of montelukast has on exercise induced bronchoconstriction correlates with the effect it has after 8 weeks of treatment.
The analysis of protease activity from saliva and the salivary biofilm, using these substrates, may provide a new layer of information useful in the discovery of prognostic markers with respect and related to the histopathological features of oral…
Our hypothesis is that the 30 day PPG based AF detection algorithm is at least equivalent to the 3 day Holter evaluation for the detection of paroxysmal atrial fibrillation
Vibrotactile feedback from a 'smart' fork reduces the eating rate of a teenage girl suffering from brain damage that causes her not to detect hunger or satiation
radiological factors for DRUJ instability may account for DRUJ instability in patients after a consolidated distal radius fracture with negative influence on outcome
This study aims to increase the implementation of smoking cessation group trainings with financial incentives among Dutch companies by developing an implementation strategy that will be tested, evaluated and adapted multiple times. We hypothesize…
Presence of postural instability and gait dissorder PIGD (gait disorders, balance impairment, falls, fal-related injuries and FOG) are an important and disabling feature of idiopathic Parkinson’s disease (PD) where the level of functional ability is…
We hypothesize there is an immunological component underlying chronic pouchitis which might be similar to that seen in UC. Therefore, we believe tofacitinib might be an effective treatment for these patients as well.
The Maastricht brace is a new develwoped thoracolumbar brace that improves wearability and quality of life, while maintaining efficiency and function
In patients with WAD the strength of the relationship between self reported disability and work capacity is weak to moderate (correlation coefficient between r=0.25 and r=0.75). Work capacity and performance can be predicted with the help of…
The monitoring performance of a wireless alternative for cardiorespiratory monitoring in neonates is equivalent (non-inferior) compared to routine monitoring with adhesive electrodes.
We hypothesize that the underlying mechanisms of the varying response in multiple parameters within an individual can be attributed to variability in the causal path between drug administration, drug tissue distribution, and tissue receptor…