819 resultaten
What is the effect of the systemic antibiotic therapy on the number and diversity of specific bacterial groups in fecal samples of pediatric patients with cancer?
We hypothesize that several parameters, measured with a wrist-worn data logger, will be predictive for a heart failure event. Parameters which are taken into account are: heart rate, activity count, energy expenditure, but also parameters which are…
The invasive bacteria Shigella and entero-invasive E.coli (EIEC) that cause gastro-enteritis, are genetically related and share an infection mechanism. In the Netherlands, Shigellosis is a notifiable disease, while infections with EIEC are not. With…
Information on the dynamics and shape of the device and how these change over time will improve our understanding about the fixation and/or sealing of the device, which may help in stent selection and in designing stent grafts that are more durable.
To determine the influence of optical quality on perimetry for phakic and pseudophakic healthy and glaucoma patients. To determine the influence of CLE on perimetry and optical quality for PAC patients.
The hypothesis is that an increased level of dysfunctional modes at baseline predicts lower CBT success (i.e., smaller reduction of symptoms). The second hypothesis is that an increased level of healthy modes at baseline predicts higher CBT success…
We predict that matching user needs and characteristics with feedback properties increases chances of sustained use of the intervention, as well as eating behaviour change. Furthermore, greater social sharing of platform results (both on- and…
The objective of the study is to identify all subjective and objective outcome measurements which have been used in TMC-OA trials and classify them according to the OMERACT core set and the ICF categories.
By increasing endoscopist's proximal serrated polyp detection rate (PSPDR) it will lower the incidence of postcolonoscopy colorectal carcinoma (PCCRC).
The aim of this observational study is to investigate the relationship between orthostatic hypotension and the rate of successful rehabilitation. A previous study showed that orthostatic hypotension increased the risk for successful rehabilitation,…
In this pilot study we want to look at different aspects of radiation damage, including effects on microvasculature, blood-brain barrier function and white matter changes. We hypothesize that combining these different imaging modalities (MRI and PET…
personality traitsinfluence the assessment of echocardiography images with respect to evaluation of LV EF and image quality.
The aim of this study is twofold: 1)To assess the effectiveness of a CPG converted into a CDSS, in actually preventing the development of WSLs during orthodontic treatment with fixed appliances compared to usual preventive measures. 2)To evaluate…
Part A The main objective of this part of the study is to develop a pharmacokinetic model for [18F]PSMA. Furthermore, use of simplified quantitative methods and procedures will be performed and validated against full quantitative kinetic measures,…
That intermuscular dissection of polyps suspected of deep submucosal invasive carcinoma can result in the radical (R0) excision of > 85% of the carcinomas, and that the risk of local recurrence is below 4%.
With this study we want to test two new modules of a chair specialised for elderly and test whether these new modules improve skin vitality and doe not disturb the users comfort. The new modules apply automatic changes in seating posture after a…
This clinical trial will determine the optimal dose of cRGD-ZW800-1 and investigate the feasibility of intraoperative FLI to adequately assess tumor margins in patients with oral cancer.
Cinacalcet is able to control hypercalciemia due to hyperparathyreoidism after renal transplantation ergo avoiding surgical removal of parathyroidtissue without jeopardizing renal function or eliciting serious adverse events.
We aim to validate Massive Parallel Sequencing in Primary Ciliary Dyskinesia (PCD) and identify novel disease causing mutations in the Dutch PCD population.