72 resultaten
Cultured mesenchymal stem cells differentiated into osteoblasts and seeded on scaffolds can induce bone formation.
urge incontinence is caused by overactivity of the detrusor muscle of the urinary bladder. Electrical stimulation of the pelvic floor muscles can suppress detrusor overactivity. The miniaturo tm-i system is designed to deliver mild electrical…
The optimal management of locoregionally advanced NSCLC is evolving. Multimodality treatment is rapidly becoming the most common approach to stage III NSCLC. ASCO guidelines recommend initial chemotherapy (platinum-based, 2 or 3 cycles) combined…
Comparison of two new techniques for detection of small bowel pathology: MR enteroclysis and videocapsule enteroscopy with double-balloon enteroscopy with respect to diagnostic yield, accuracy of findings, and patient preference.
HIV infected patients receiving HAART have an increased risk for cardiac events/disease. In HAART naive patients increased arterial stiffness is substrate for this higher risk. In this study we investigate whether increased risk for cardiac events…
To identify high risk patient groups for development of knee osteoarthritis (OA) in a cohort 9-10 years after meniscus, cruciate ligament and cartilage lesions.
The principal aim of this research project is to establish the origin of increased echogenicity in the thalami and basal ganglia (ED/TDG), an ultrasonographic finding fequently encountered in very preterm infants. It is not known whether ED/TBG is a…
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As EGFR plays a role in pathogenesis of both pulmonary arterial hypertension and systemic sclerosis, EGFR inhibition will lead to beneficial effects in disease course.
Risk of chronic PTSD after ASD diminishes with an early intervention (CBT) that attempts to modify cognitive appraisals.
The computer-tailored health information in combination with personal counselling leads to: 1. Improvement of health behaviors; 2. Improvement of parental satisfaction with well-child care visits; 3. Improvement of well-child care provider…
1. Effectsizes of the psychotherapeutic treatments vary between 0.5 and 2.0; 2. A lower dosage of psychotherapeutic treatment is mainly related to symptomatic improvement, while a higher a dosage is also related to structural and functional…
Excluding PE by a CDR indicating PE unlikely, assessed by the Wells simplified decision rule, combined with a normal D-dimer is safe and efficient.
The aim of this study is to explore the incidence of MTX related gastro-intestinal in a large cohort of JIA patients. Secondly, we want to investigate the effect of psychological behavioural therapy or switch to parenteral MTX dosing to ameliorate…
On short-term, the Combined treatment is expected to be superior to either mono-treatment. On long-term it is expected that CBT will prove to be more durable and that patients in the SSRI will require more mental health care during the one-year…
In view of good pre-clinical and clinical results, it is thought that patients with renal cell cancer will benefit from BAY 43-9006 in a neoadjuvant setting.We anticipate a benefit with the treatment of BAY 43-9006 when there is a tumour reduction…
Optimum timing of surgery for macula off rhegmatogenous retinal detachment can be determined in more detail by taking both duration and height of macular detachment into account.
The carrier frequence of hemoglobinopathies is > 0,05 and screening for primary prevention is cost-effective.
After allogeneic stem cell transplantation (SCT) the hematopoiesis is from donor origin. Laboratory and animal studies suggests that de dendritic cells of host origin are important in inducing graft versus myeloma effect and graft versus host…
The large implementation of SMOCC will be more (cost-) effective than the usually applicated basic dissemination strategies for guidelines.