168 resultaten
Flumazenil is a substrate of P-glycoprotein at the blood-brain barrier.
To gain more insight into the pathogenetic processes involved in Sjogrens Syndrome(SS) bij analyzing the infiltrate and structural changes in salivary glands of SS patients and compare these findings to those in other (aspecific) inflammatory and…
Intra-operatieve fluorescente beeldvorming van schildwachtklieren bij baarmoederhalskankerpatienten.
Fluorescent near-infrared imaging can accurately detect sentinel lymph nodes non-invasively during lymphadenectomy in cervical cancer patients.
We therefore hypothesize that FABP/Claudin levels may be used as a diagnostic tool for the identification of intra-abdominal injury necessitating surgery and as a prognostic marker for the development of SIRS/MOF (and morbidity and mortality) in…
There have been several studies that showed a possible positive effect of electrical stimulation on wound healing. One of the working principles is increasing blood flow. This could mean that by giving frequent electrical stimulation on the foot and…
There is clear medical need in pediatric high-grade MDS and JMML to control disease pre-SCT without the disadvantages associated with intensive chemotherapy. So far no agents have been successfully applied in this window, or are specifically…
1. The point of the skin with best possible transcutaneous nerve stimulation correlates with the point of the skin most superficial to the nerves stimulated within a range of 3 mm; 2. Ultrasound will reveal a significant number of sensitive…
The objective of the study is to identify factors associated with anterior knee pain after primary total knee replacement.
What is the prevalence of dysplasia or carcinoma in patients with Crohn's disease that undergo surveillance endoscopy with chromoendoscopy-guided confocal laser endomicroscopy?
The effectiveness of the experimental conditions depends on the motivational characteristics of the person. 1. The sequential condition will lead to 10% behavior change in one behavior after two years, if a person is only motivated to change one…
Gaining knowledge on human responses against the influenza virus will help us in treating influenza infections and lead to more effective vaccines. Additionally, it might also lead to identification of individuals that have a high risk of morbidity…
The nephrotoxicity caused by cisplatin is of great concern both in that it is dose-limiting and can be detrimental to the patient. Much work has been done to reduce or prevent this damage to renal cells, however to date the best approach has reduced…
To test the accuracy of dynamic MRI with T1 mapping in patients with CD and compare this with know parameters such as CDEIS, CRP and CDAI.
Research questions and accompanying hypotheses: 1. Is there a difference in fatigue resistance of the knee extensor muscles between patients with PPS and able-bodied control subjects and is this related to aerobic capacity? Hypothesis: It is…
We hypothesize that individual instruction of parents and patients with hemophilia at home by a hemophilia nurse will lead to increase in quality of life parameters. Quality of life will increase due to a better understanding of the disease and its…
Genestein inhibits the synthesis of heparan sulphate and can possibly slow down disease progression in Sanfilippo Syndrome patients.
The aim of this project is to determine optimal communication strategies for prognostic disclosure in the palliative phase of breast cancer from a patient perspective. Study 1: To explore breast cancer survivors’, healthy women’s and oncologists’…
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Reducing postoperative pain with a mini-sling.
Is there a difference in the recurrence rate if you treat a cyst or abscess of the bartholin gland with a marsupialization or placement of a word catheter.