222 resultaten
Current clinical practice is to perform response evaluation, i.e. examination under general anesthesia (EUA), routinely at 3 months after the end of treatment in patients who underwent chemoradiation for oropharyngeal cancer. Due the high response…
Submucous fibroids are known to be related to heavy menstrual bleeding (HMB), dysmenorrhea and fertility problems. Transcervical resection of fibroids (TCRM) is a widely implemented treatment for submucous fibroids, to be precise FIGO PALM-COEIN…
We hypothesize that group medical appointments will enhance adherence to treatment and self-efficacy in patients with sickle cell disease, as well as increase quality of life, and satisfaction with the treating physician and nurse. When performing…
1. Alcohol marketing influences youth drinking 2. The following factors moderate of mediate the relationship between marketing & drinking: a. Personal relevance of advertisements, b. Sociability, parental guidance in understanding TV and…
In this protocol we will study the value of selinexor as the third agent based on its unique mechanism of action and reported synergy with bortezomib in patients with progressive or refractory MM.
Usage of the 'Moveosiphon' sonothermal sink disinfection device prevents leads to a persistant decrease in colonization with multiresistant Pseudomonas aeruginosa
We expect that when the developed checklist will be used in de diagnostic proces of children with developmental and/or behavioral disability, the use of pediatric care will be more efficiently used. Over and underdiagnoses of a causal somatic…
The main hypothesis is that normo-ovulatory women with a deleterious BRCA mutation have lower levels of AMH compared to normal controls, with at least a difference of 0.90 ng/ml, suggesting an effect size of approximately five years in menopausal…
This study has 2 primary objectives: 1) To determine the time point of induction of VEGF expression in the tumour tissue of oesophagus carcinomas during chemoradiation. 2) To determine whether the tumour promoting effects of this induction of VEGF…
To investigate whether patients prefer to be approached by mailed questionnaires for annual follow-up assessment after PCI procedures versus telephone interviews or email-based follow-up
The primary objective is to estimate the frequency of subjects with at least one apnoeic episode, defined as respiratory rate ≤6, detected using the respiR8® device for up to 6 hours after surgery. Apnoea is defined as 10 seconds of no breathing…
We hypothesize that age-related changes in hepatic and intestinal drug metabolism affect the pharmacokinetics of paracetamol.
Low-molecular-weight heparins (LMWHs) are frequently used in the prophylaxis and therapy of venous thromboembolism (VTE) and the prophylaxis of arterial thromboembolism. LMWHs are mainly excreted by the kidneys and may accumulate in patients with…
EUS-guided fiducial placement in pancreatic tumors is a technically successfull and safe procedure. After placement fiducials can be successfully used for highly-accurate delivery of image-guided radiotherapy.
Aim of the study is to receive reference ranges for a plasma and a whole blood thrombingeneration assay.
The main objective is to determine the early and late survival and reoperation outcome of VSARR in patients suffering from aortic root aneurysm with or without aortic regurgitation. Furthermore, we will evaluate the quality of using a SF-36 form.…
Many studies have shown that children with clefts are at high risk of developing feeding disorders. Especially children with a cleft lip and palate (CLP) or cleft palate only (CP) are subject to feeding disorders. Our evidence based results can help…
We propose to evaluate the beneficial effects of adding a contingengy management (CM) intervention, aimed at a reduction of cocaine consumption, to the current heroin-assisted treatment. This intervention – combined heroin-assisted treatment plus CM…
Goal: To investigate what the perceived role in treatment decision making is in patients with a displaced midshaft clavicular fracture. Do patients prefer a more/less active role in making this decision?