222 resultaten
• Participants in the experimental condition (i.e., mindfulness exercises) will experience a larger decrease on the implicit negative affect scale of the Implicit Positive and Negative Affect Test compared to the waitlist condition • Participants…
Electrophysiological connectivity between ATN and cortical zones involved in the epilepsy of the patient in question relates to treatment response
We hypothesize that HFOs recorded non-invasively with MEG and scalp EEG are biomarkers of disease activity like iEEG HFOs
To establish the yield of pancreatic cyst surveillance, based on the recently published European consensus statement, and to identify possible alternative, more (cost) effective, surveillance strategies.
A nutrient rich diet can improve immunological functions and reduce respiratory infections
Test weighing using a double-check weighing method is precise in determining infant intake: in more than 90% of weighings test weighing will be within 5ml of the actual amount drunk
Both hypoxia and hyperoxia can lead to organ damage in preterm infants. For this reason the transcutaneously measured oxygen saturation (SpO2) is kept within a range between 86% and 95%. Hypoxia is mainly caused by immature or impaired control of…
WOMET is has acceptable internal consistency, test-retest reliability, floor and ceiling effects, criterion validity, and construct validity. The WOMET is expected to be responsive to change.
Pulse oximetry screening for critical congenital heart defects in the Netherlands is intermediate sensitive, highly specific and cost-effective.
Sarcoidosis (SA) is a rare systemic disease that is characterized by the formation of granulomas. It can affect any organ in the body. Somatostatin is a peptide hormone that regulates neuroendocrine processes but it also is an intersystem…
For patients with stage III-IV irresectable melanoma who have at most 3 metastases, the tumor can be reduced in size by treating with dabrafenib and trametinib for 8 weeks. After this reduction, complete surgery of the tumor could be made possible.
We hypothesize that the circulatory and cardiac effects of TEA will be most pronounced during circumstances of increased sympathicotonus, which will be induced by an exercise test on a bicycle.
The TORCH screen is often requested by gynecologists, but there rarely is a clinical relevant outcome. Isn’t it better to reduce the test indications or the number of tested infections to make the test more cost effective and clinical relevant? And…
To evaluate the effects of thoracic epidural anaesthesia (TEA) with general anaesthesia on mean systemic filling pressures, arterial- and venous resistance and cardiac output. To assess the hemodynamic effects of vasopressors and fluid loading under…
The primary objective of this study is to obtain clinical proof of principle that the Addition of a PgP/BCRP inhibitor increases CNS concentrations of tyrosine kinase inhibitors by inhibition of drug efflux transporter function in the blood brain…
This study tests the hypothesis that age has an effect on prefrontal brain activity, measured by fNIRS and EEG, during a cognitive paradigm assessing proactive response inhibition and working memory. The results of the fNIRS-EEG study will be…
To test wheter the Enose can differentiate between pneumonia (or exacerbation of COPD, asthma exacerbation or respiratoiry infection) by viral of bacterial infection.
In this protocol we will study the value of selinexor as the third agent based on its unique mechanism of action and reported synergy with bortezomib in patients with progressive or refractory MM.