28 resultaten
We hypothesize that it is possible to culture circulating tumor cells obtained by leukapheresis into organoids.
Exploration of the effects of AAT in adults with an Autism Spectrum Disorder (because this study has an explorative character, there is no hypothesis formulated)
Family Group Conferences will improve disability-management self-efficacy and participation in patients with amputation, acquired brain injury and spinal cord injury and their relatives
The Victoria modules are thought to have a positive effect on acknowlegdement for adversities and risk awareness. This can be used to take acceptable risks in rehabilitation process. This will then lead to more societal participation and less…
We hypothesize a priori that the Dutch NAT: PD-HF will be a feasible and acceptable tool to identify palliative care needs in patients with CHF and will initiate appropriate management.
We expect that the Dutch language versions of the AOFAS Ankle-Hindfoot and the AOFAS Midfoot score will have adequate measurement properties (e.g. reliability and validity).
We hypothesize that age-related changes in hepatic and intestinal drug metabolism affect the pharmacokinetics of midazolam.
intravenous immunoglobulins will induce a fast and effective response in patients with newly diagnosed idiopathic inflammatory myopathies. Also, the treatment will be generally safe. Furthermore, this pilot study will show feasibility with respect…
The main outcome is the identification of clinical, biochemical, and genetic factors associated with resilience to cognitive decline in extreme elderly subjects. At baseline we will test the association between cognitive resilience and amyloid…
In TMD patients with concomitant headache, t is hypothesized that treatment of the TMD complaints will have a positive effect on the headache as well. The effect size is expected to depend on the type of headache, with the strongest effect for…
Urinary and (peripheral and central) intravenous catheters are widely used in hospitalized patients, although some serious complications can occur with the use of these catheters. Up to 56% of the catheters do not have an appropriate indication. The…
1. High school Freshman develop less positive attitudes towards substance use after participation in Fresh Start than high school freshman in the waitlist control condition. 2. Fresh Start is more effective when it is implemented at the beginning of…
Because of the increasing incidence of work-related musculoskeletal disorders of the upper extremities, the UEWD questionnaire was developed as a riskassessment that takes less time and less expenses then an observation. The aim of this study is to…
To evaluate the validity, reproducibility and scale functioning of the Dutch clinician-based Constant-Murley (CM) score and of a Dutch patient-derived Constant-Murley score in patients with shoulder arthroplasty. To define the smallest detectable…
- The enhanced prism spectacle (MD-clip) will increase the Quality of Life in patients with severe macula degeneration - The MD-clip will increase vision in patients with severe macula degeneration
We expect that treating patients with the IlluminOss® System will result in excellent recovery
The purpose of this study is to evaluate toxicity and feasibility of MRI-guided focal salvage high-dose-rate brachytherapy (HDR-BT) in patients with locally recurrent prostate cancer. In comparison with whole-gland salvage techniques, focal…
The purpose of this study is: 1. To investigate the effectiveness of teacher training in Classroom Pivotal Response Teaching (CPRT) on teacher-created opportunities 2. To investigate the effectiveness of CPRT on children's communication…
Our hypothesis is that MRKH patients are exposed to high concentrations AMH in utero, coming from their male co-twin (possible vanished twin). This AMH-exchange is possible because of intrauterine blood exchange between two fetuses. This blood…