637 resultaten
To retrospectively study Inotuzumab ozogamicin (InO) safety and toxicities in infants and younger children with relapsed or refractory ALL To study rates of response (morphologic response and minimal residual disease status) after therapy with InO
1. Sales data of VRPs in the canteens will increase during phases in which the designated products are nudged. 2. Sales data of SSBs in the vending machines will decrease during phases in which the designated products are nudged.
to improve the medical care on long term follow up
Gut dysbiosis drives disease processes driving morbidity and mortality in acute pancreatitis, such as infected pancreatic necrosis, and (persistent) multiple organ failure. A decrease in commensal members of the bacterial microbiome allows for…
We hypothesize that high interval physical exercise changes the contribution of adipose tissue and peripheral muscle to human NAFLD and aberrant glucose metabolism via gutmicrobiota mediated plasma metabolites.
Aim of the MANCO study is to establish for once and for all that monitoring the effect of heparin during NCVI is essential to ensure the individual patient of safe and tailor-made anticoagulation. Not measuring the effect of the administered heparin…
It is hopthesized that a multidimensional implementation approach with multiple interventions integrated in the usual care will improve physical behaviour during hospitalization
People from more disadvantaged backgrounds face barriers in accessing post-diagnostic dementia care.
Kidney transplantation is the only treatment offering long-term benefit to patients with chronic kidney failure. Urological complications after kidney transplantation, such as urinary leakage and ureteral strictures, are associated with significant…
Patient education on extended anticoagulation pros and cons: a journey app in venous thromboembolism
Our hypothesis is that patients whom receive targeted information about VTE and (extended) anticoagulation treatment with the 'patient journey app' on a daily basis in the week preceding their hospital visit will be more satisfied with the…
Breast cancer is the most common type of female cancer worldwide. Early detection has proven to have a positive influence on the prognosis and survival rate. An important aid in the detection and diagnosis of breast cancer is the use of medical…
We hypothesize that depletion of carnitine occurs during infusion of oxaliplatin, due to increased renal loss. This secondary carnitine deficiency may contribute to the development of CIPN.
Primary hypothesis: Octane concentrations in exhaled breath facilitate early detection of ARDS in ICU patients. Secondary hypotheses: - ARDS resolution is associated with a decrease in octane in exhaled breath. - Additional biomarkers of ARDS can be…
It is hypothesized that taste and smell disturbances are common among GIST patients using TKIs.
DBS leads to a symptom reduction in patients with OCD
We hypothesise that the diet over time has become healthier and more sustainable. Our current study was set up to (1) identify the differences in food consumption and nutritional quality over the course of 20 years in the Netherlands using the…
It is hypothesised that compared to waiting list control condition, participants in the intervention improve their diet and physical activity on the short (6 months after baseline) and long-term (12 months after baseline; when the participant…
To investigate the feasibility and safety of the DMUA-HIFU system for treatment of atherosclerotic plaques.
We hypothesize that remote home monitoring can detect post-discharge complications early and might prevent hospital readmissions.
Current standard treatments for symptomatic benign thyroid nodules (SBTN) are surgery or radioactive iodine. However, these interventions pose a risk to an otherwise healthy person. Therefore, minimally invasive alternatives have been explored.…